QuickView for CAPG (gene)

Gene Symbol:

CAPG Homo sapiens

Full name:

capping actin protein, gelsolin like

Synonyms:

AFCP, HEL-S-66, MCP, macrophage-capping protein, actin-regulatory protein CAP-G, capping protein (actin filament), gelsolin-like, epididymis secretory protein Li 66, gelsolin-like capping protein

Genomic Location:

Chr 2: 85475382-85491187

Description:

This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control...

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This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTANTCA_UNKNOWN ,  NFAT_Q6 ,  CIZ_01 ,  GGGAGGRR_MAZ_Q6 ,  PTF1BETA_Q6

Cytogenetic Map:

2p11.2

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