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QuickView for CAPPB (gene)


Gene Symbol:
CAPZB Homo sapiens Homo sapiens
Full name:
capping actin protein of muscle Z-line beta subunit
Synonyms:
CAPB, CAPPB, CAPZ, F-actin-capping protein subunit beta, capZ beta, capping protein (actin filament) muscle Z-line, beta
Genomic Location:
Chr 1: 19537860-19684579
Description:
This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Schizosaccharomyces pombe Danio rerio Bos taurus Gallus gallus Canis lupus familiaris
External Links:
Entrez Gene
Cytogenetic Map:
chr 1
1p36.13





GO Molecular Function

actin binding | actin filament binding | cadherin binding | protein-containing complex binding | cytoskeletal protein binding | cell adhesion molecule binding | protein binding

GO Biological Process

regulation of supramolecular fiber organization | cell morphogenesis | actin filament-based process | regulation of cell morphogenesis | antigen processing and presentation | negative regulation of protein complex disassembly | actin cytoskeleton organization | establishment of localization | negative regulation of cellular process | regulation of organelle organization | regulation of actin polymerization or depolymerization | intracellular transport | cellular process | localization | hemostasis | establishment of localization in cell | regulation of cellular process | regulation of protein complex assembly | cellular component organization | regulation of actin filament length | response to stimulus | response to stress | cellular localization | antigen processing and presentation of exogenous peptide antigen via MHC class II | regulation of cellular component size | blood coagulation | actin filament capping | regulation of cell projection assembly | antigen processing and presentation of peptide antigen via MHC class II | regulation of actin cytoskeleton organization | regulation of actin filament organization | regulation of protein complex disassembly | wound healing | negative regulation of actin filament polymerization | vesicle-mediated transport | negative regulation of filopodium assembly | regulation of actin filament polymerization | regulation of actin filament depolymerization | Golgi vesicle transport | regulation of filopodium assembly | regulation of protein depolymerization | coagulation | antigen processing and presentation of exogenous antigen | negative regulation of protein polymerization | negative regulation of cell projection organization | response to wounding | anatomical structure development | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | regulation of body fluid levels | negative regulation of cytoskeleton organization | negative regulation of protein complex assembly | barbed-end actin filament capping | cytoskeleton organization | negative regulation of actin filament depolymerization | ER to Golgi vesicle-mediated transport | anatomical structure morphogenesis | regulation of developmental process | developmental process | organelle organization | regulation of lamellipodium assembly | antigen processing and presentation of peptide antigen | negative regulation of supramolecular fiber organization | regulation of actin filament-based process | regulation of cell projection organization | immune system process | regulation of cellular component organization | regulation of cytoskeleton organization | multicellular organismal process

GO Cellular Component

supramolecular fiber | F-actin capping protein complex | sarcomere | cell | myofibril | cytoplasm | intracellular organelle | actin cytoskeleton | WASH complex | contractile fiber | protein-containing complex | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cytosol | actin filament | cytoskeleton | intracellular | supramolecular complex