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QuickView for CAPZA2 (gene)


Gene Symbol:
CAPZA2 Homo sapiens Homo sapiens
Full name:
capping actin protein of muscle Z-line alpha subunit 2
Synonyms:
CAPPA2, CAPZ, F-actin-capping protein subunit alpha-2, F-actin capping protein alpha-2 subunit, capZ alpha-2, capping protein (actin filament) muscle Z-line, alpha 2
Genomic Location:
Chr 7: 116289799-116346549
Description:
The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end.
Orthologs:
Mus musculus Rattus norvegicus Saccharomyces cerevisiae Macaca mulatta Gallus gallus Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 7
7q31.2


Transcripts Names
NM_006136
XR_001744882
Protein Names
A4D0V4
P47755



GO Molecular Function

actin binding | actin filament binding | protein-containing complex binding | cytoskeletal protein binding | protein binding

GO Biological Process

regulation of supramolecular fiber organization | actin filament-based process | antigen processing and presentation | negative regulation of protein complex disassembly | actin cytoskeleton organization | establishment of localization | negative regulation of cellular process | defense response | regulation of organelle organization | regulation of actin polymerization or depolymerization | intracellular transport | cellular process | localization | hemostasis | establishment of localization in cell | regulation of cellular process | regulation of protein complex assembly | cellular component organization | regulation of actin filament length | response to stimulus | response to stress | cellular localization | antigen processing and presentation of exogenous peptide antigen via MHC class II | regulation of cellular component size | cellular component assembly | blood coagulation | actin filament capping | antigen processing and presentation of peptide antigen via MHC class II | regulation of actin cytoskeleton organization | regulation of actin filament organization | regulation of protein complex disassembly | wound healing | negative regulation of actin filament polymerization | vesicle-mediated transport | regulation of actin filament polymerization | regulation of actin filament depolymerization | Golgi vesicle transport | regulation of protein depolymerization | coagulation | antigen processing and presentation of exogenous antigen | protein-containing complex assembly | negative regulation of protein polymerization | response to wounding | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | regulation of body fluid levels | negative regulation of cytoskeleton organization | immune response | negative regulation of protein complex assembly | barbed-end actin filament capping | cytoskeleton organization | negative regulation of actin filament depolymerization | ER to Golgi vesicle-mediated transport | organelle organization | innate immune response | antigen processing and presentation of peptide antigen | negative regulation of supramolecular fiber organization | regulation of actin filament-based process | immune system process | regulation of cellular component organization | regulation of cytoskeleton organization | multicellular organismal process

GO Cellular Component

brush border | F-actin capping protein complex | actin cortical patch | cell | cytoplasm | cortical cytoskeleton | intracellular organelle | actin cytoskeleton | protein-containing complex | vesicle | extracellular exosome | endocytic patch | cytoplasmic region | cortical actin cytoskeleton | extracellular region | cell cortex | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | cytosol | cytoskeleton | intracellular | membrane