QuickView for CASP6 (gene)

Gene Symbol:

CASP6 Homo sapiens

Full name:

caspase 6

Synonyms:

MCH2, caspase-6, apoptotic protease MCH-2, caspase 6, apoptosis-related cysteine peptidase, caspase 6, apoptosis-related cysteine protease

Genomic Location:

Chr 4: 110829234-110844078

Description:

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that ...

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This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

miRNA binding sites
(Source: miRecords):

hsa-miR-125b Targeted Genes

Cytogenetic Map:

4q25

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