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QuickView for CBR1 (gene)


Gene Symbol:
CBR1 Homo sapiens Homo sapiens
Full name:
carbonyl reductase 1
Synonyms:
CBR, SDR21C1, hCBR1, carbonyl reductase [NADPH] 1, 15-hydroxyprostaglandin dehydrogenase, NADPH-dependent carbonyl reductase 1, carbonyl reductase (NADPH) 1, prostaglandin 9-ketoreductase, prostaglandin-E(2) 9-reductase, short chain dehydrogenase/reductase family 21C member 1
Genomic Location:
Chr 21: 36364155-36367332
Description:
The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 21
21q22.12


Transcripts Names
NM_001757
NM_001286789
Protein Names
Q3LHW8
P16152
B2RBZ7



GO Molecular Function

oxidoreductase activity, acting on NAD(P)H | oxidoreductase activity, acting on CH-OH group of donors | prostaglandin-E2 9-reductase activity | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | catalytic activity | carbonyl reductase (NADPH) activity | 15-hydroxyprostaglandin dehydrogenase (NADP+) activity | protein binding | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | oxidoreductase activity

GO Biological Process

oxidoreductase activity, acting on NAD(P)H | oxidoreductase activity, acting on CH-OH group of donors | prostaglandin-E2 9-reductase activity | cell differentiation | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | cellular process | unsaturated fatty acid biosynthetic process | tissue development | epithelium development | icosanoid biosynthetic process | cellular lipid metabolic process | monocarboxylic acid metabolic process | cyclooxygenase pathway | cellular biosynthetic process | lipid metabolic process | small molecule metabolic process | vitamin K metabolic process | carbonyl reductase (NADPH) activity | fatty acid biosynthetic process | biosynthetic process | lipid biosynthetic process | 15-hydroxyprostaglandin dehydrogenase (NADP+) activity | long-chain fatty acid metabolic process | drug metabolic process | carboxylic acid metabolic process | vitamin metabolic process | anatomical structure development | metabolic process | oxidation-reduction process | prostaglandin metabolic process | organic substance metabolic process | fatty acid metabolic process | icosanoid metabolic process | organic acid metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | developmental process | prostaglandin biosynthetic process | epithelial cell differentiation | cellular metabolic process | oxidoreductase activity | arachidonic acid metabolic process

GO Cellular Component

cell | cytoplasm | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cytosol | intracellular