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QuickView for CC-CKR-3 (gene)


Gene Symbol:
CCR3 Homo sapiens Homo sapiens
Full name:
C-C motif chemokine receptor 3
Synonyms:
CC-CKR-3, CD193, CKR3, CMKBR3, C-C chemokine receptor type 3, C-C CKR-3, CC chemokine receptor 3, CCR-3, b-chemokine receptor, chemokine (C-C motif) receptor 3, eosinophil CC chemokine receptor 3, eosinophil eotaxin receptor
Genomic Location:
Chr 3: 46258692-46283166
Description:
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3
3p21.31





GO Molecular Function

cytokine binding | transmembrane signaling receptor activity | G-protein coupled receptor activity | chemokine binding | signaling receptor activity | G-protein coupled chemoattractant receptor activity | cytokine receptor activity | protein binding | C-C chemokine receptor activity | peptide receptor activity | chemokine receptor activity | G-protein coupled peptide receptor activity | C-C chemokine binding

GO Biological Process

response to cytokine | cell motility | intracellular signal transduction | positive regulation of developmental process | positive regulation of epithelial cell proliferation | chemokine-mediated signaling pathway | defense response | cellular chemical homeostasis | positive regulation of endothelial cell proliferation | cellular process | localization | cellular homeostasis | interspecies interaction between organisms | regulation of angiogenesis | regulation of cellular process | regulation of cytosolic calcium ion concentration | calcium ion homeostasis | G-protein coupled receptor activity | regulation of vasculature development | response to stimulus | response to stress | regulation of cell proliferation | G-protein coupled receptor signaling pathway | cell chemotaxis | metal ion homeostasis | locomotion | cell migration | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | cytokine-mediated signaling pathway | G-protein coupled chemoattractant receptor activity | second-messenger-mediated signaling | cellular response to cytokine stimulus | cation homeostasis | cytokine receptor activity | cellular cation homeostasis | cell communication | inflammatory response | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | viral process | calcium-mediated signaling | response to organic substance | cell surface receptor signaling pathway | chemical homeostasis | cell adhesion | immune response | regulation of endothelial cell proliferation | ion homeostasis | C-C chemokine receptor activity | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | chemokine receptor activity | signaling | G-protein coupled peptide receptor activity | regulation of epithelial cell proliferation | regulation of developmental process | cellular defense response | cellular metal ion homeostasis | immune system process | cellular response to organic substance | chemotaxis | divalent inorganic cation homeostasis | positive regulation of angiogenesis | signal transduction

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | external side of plasma membrane | cytoplasm | plasma membrane | integral component of plasma membrane | cell periphery | cell surface | intracellular | membrane | intrinsic component of plasma membrane