QuickView for CCL11 (gene)

Gene Symbol:

CCL11 Homo sapiens

Full name:

C-C motif chemokine ligand 11

Synonyms:

SCYA11, eotaxin, chemokine (C-C motif) ligand 11, eosinophil chemotactic protein, eotaxin-1, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)

Genomic Location:

Chr 17: 29636800-29639312

Description:

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemo...

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This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PBX1_02

Cytogenetic Map:

17q12

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