QuickView for CCL1 (gene)

Gene Symbol:

CCL1 Homo sapiens

Full name:

C-C motif chemokine ligand 1

Synonyms:

I-309, P500, SCYA1, SISe, TCA3, C-C motif chemokine 1, T lymphocyte-secreted protein I-309, chemokine (C-C motif) ligand 1, inflammatory cytokine I-309, small inducible cytokine A1 (I-309, homologous to mouse Tca-3)

Genomic Location:

Chr 17: 29711512-29714365

Description:

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemo...

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This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ATAAGCT_MIR21

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-21

Cytogenetic Map:

17q12

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