QuickView for CCNB2 (gene)

Gene Symbol:

CCNB2 Homo sapiens

Full name:

cyclin B2

Synonyms:

HsT17299, G2/mitotic-specific cyclin-B2

Genomic Location:

Chr 15: 57184612-57204536

Description:

Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi...

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Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF4_Q6 ,  AACTTT_UNKNOWN

Cytogenetic Map:

15q22.2

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