QuickView for CCT3;jsessionid=465FFD5B164A3A29E5CB79D5E802CE66 (gene)
- Gene Symbol:
- CCT3
Homo sapiens - Full name:
- chaperonin containing TCP1 subunit 3
- Synonyms:
- CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5, T-complex protein 1 subunit gamma, T-complex protein 1, gamma subunit, TCP1 (t-complex-1) ring complex, polypeptide 5, chaperonin containing TCP1, subunit 3 (gamma), hTRiC5
- Genomic Location:
- Chr 1: 154545376-154574819
- Description:
-
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Schizosaccharomyces pombe , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
1q22
GO Molecular Function
nucleic acid binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | small molecule binding | RNA binding
GO Biological Process
regulation of telomere maintenance via telomerase | positive regulation of macromolecule biosynthetic process | positive regulation of cellular component organization | regulation of cellular localization | protein stabilization | regulation of localization | establishment of localization | regulation of organelle organization | positive regulation of cellular biosynthetic process | cellular process | localization | regulation of telomerase RNA localization to Cajal body | positive regulation of nitrogen compound metabolic process | cell recognition | regulation of cellular process | regulation of metabolic process | positive regulation of establishment of protein localization to telomere | cellular component organization | regulation of cellular protein localization | positive regulation of cellular protein localization | toxin transport | sperm-egg recognition | reproduction | cellular component assembly | positive regulation of telomere maintenance via telomere lengthening | reproductive process | positive regulation of organelle organization | regulation of protein stability | regulation of telomere maintenance | binding of sperm to zona pellucida | positive regulation of chromosome organization | positive regulation of cellular metabolic process | cell-cell recognition | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | positive regulation of protein localization to nucleus | fertilization | positive regulation of telomere maintenance via telomerase | pore complex assembly | regulation of telomere maintenance via telomere lengthening | regulation of cellular metabolic process | positive regulation of DNA biosynthetic process | positive regulation of establishment of protein localization | single fertilization | positive regulation of protein localization to Cajal body | protein-containing complex assembly | regulation of establishment of protein localization | positive regulation of telomerase RNA localization to Cajal body | protein folding | regulation of chromosome organization | positive regulation of protein localization to chromosome, telomeric region | positive regulation of telomere maintenance | positive regulation of DNA metabolic process | regulation of DNA biosynthetic process | positive regulation of metabolic process | regulation of protein localization | sexual reproduction | regulation of cellular component organization | regulation of establishment of protein localization to chromosome
GO Cellular Component
supramolecular fiber | cell body | cell | microtubule | cytoplasm | intracellular organelle | protein-containing complex | zona pellucida receptor complex | plasma membrane | vesicle | chaperonin-containing T-complex | extracellular exosome | microtubule cytoskeleton | extracellular region | membrane-bounded organelle | extracellular vesicle | chaperone complex | organelle | extracellular space | cell periphery | cytosol | cytoskeleton | intracellular | myelin sheath | membrane | supramolecular complex
