QuickView for CD151 (gene)

Gene Symbol:

CD151 Homo sapiens

Full name:

CD151 molecule (Raph blood group)

Synonyms:

GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24, CD151 antigen, CD151 antigen (Raph blood group), hemidesmosomal tetraspanin CD151, membrane glycoprotein SFA-1, platelet surface glycoprotein gp27, platelet-endothelial cell tetraspan antigen 3, platelet-endothelial tetraspan antigen 3, tetraspanin-24, tspan-24

Genomic Location:

Chr 11: 822952-828835

Description:

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation,...

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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGANTCA_AP1_C ,  CATTGTYY_SOX9_B1 ,  GGGAGGRR_MAZ_Q6 ,  DBP_Q6 ,  AP1_Q4 ,  GTGCCTT_MIR506 ,  CTGCAGY_UNKNOWN ,  ISRE_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-124a

Cytogenetic Map:

11p15.5

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