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QuickView for CD19 (gene)


Gene Symbol:
CD19 Homo sapiens Homo sapiens
Full name:
CD19 molecule
Synonyms:
B4, CVID3, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, T-cell surface antigen Leu-12, differentiation antigen CD19
Genomic Location:
Chr 16: 28850761-28858164
Description:
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B l...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 16
16p11.2





GO Molecular Function

catalytic activity | phosphatidylinositol 3-kinase activity | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | transferase activity | kinase activity

GO Biological Process

positive regulation of immune response | positive regulation of release of sequestered calcium ion into cytosol | immune response-regulating signaling pathway | regulation of cellular localization | regulation of localization | phosphatidylinositol metabolic process | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | immune response-activating cell surface receptor signaling pathway | defense response | cellular chemical homeostasis | phospholipid metabolic process | cellular process | cellular homeostasis | regulation of proteolysis | regulation of protein kinase B signaling | regulation of immune response | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | cellular lipid metabolic process | calcium ion homeostasis | response to stimulus | positive regulation of immune system process | response to stress | positive regulation of cation transmembrane transport | regulation of humoral immune response | immune response-activating signal transduction | regulation of protein processing | B cell receptor signaling pathway | metal ion homeostasis | regulation of calcium ion transport into cytosol | regulation of signal transduction | positive regulation of calcium ion transmembrane transport | phosphorus metabolic process | positive regulation of protein kinase B signaling | lipid metabolic process | regulation of acute inflammatory response | regulation of gene expression | organophosphate metabolic process | cellular ion homeostasis | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | phosphatidylinositol 3-kinase activity | regulation of release of sequestered calcium ion into cytosol | phosphorylation | regulation of calcium ion transmembrane transport | regulation of complement activation | cation homeostasis | phosphate-containing compound metabolic process | lipid phosphorylation | cellular cation homeostasis | cell communication | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | lipid modification | homeostatic process | glycerolipid metabolic process | positive regulation of transport | phosphatidylinositol-4,5-bisphosphate 3-kinase activity | activation of immune response | regulation of intracellular signal transduction | cell surface receptor signaling pathway | metabolic process | chemical homeostasis | organic substance metabolic process | regulation of sequestering of calcium ion | positive regulation of ion transport | ion homeostasis | regulation of ion transmembrane transport | antigen receptor-mediated signaling pathway | regulation of cell communication | signaling | phosphatidylinositol phosphorylation | positive regulation of calcium ion transport into cytosol | regulation of ion transport | glycerophospholipid metabolic process | kinase activity | regulation of calcium ion transport | regulation of transport | cellular defense response | cellular metal ion homeostasis | immune system process | cellular metabolic process | regulation of inflammatory response | divalent inorganic cation homeostasis | positive regulation of calcium ion transport | positive regulation of signaling | signal transduction | regulation of signaling

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | external side of plasma membrane | protein-containing complex | plasma membrane | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | cell surface | membrane | intrinsic component of plasma membrane