QuickView for CD206 (gene)

Gene Symbol:

MRC1 Homo sapiens

Full name:

mannose receptor C-type 1

Synonyms:

CD206, CLEC13D, CLEC13DL, MMR, MRC1L1, bA541I19.1, hMR, macrophage mannose receptor 1, C-type lectin domain family 13 member D, human mannose receptor, macrophage mannose receptor 1-like protein 1, mannose receptor, C type 1-like 1

Genomic Location:

Chr 10: 18138358-18240097

Description:

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The pro...

View Full Description

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TAATGTG_MIR323 ,  AATGTGA_MIR23A_MIR23B

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-323

Cytogenetic Map:

10p12.33

search → result