QuickView for CD226 (gene)

Gene Symbol:

CD226 Homo sapiens

Full name:

CD226 molecule

Synonyms:

DNAM-1, DNAM1, PTA1, TLiSA1, CD226 antigen, DNAX accessory molecule-1, T lineage-specific activation antigen 1 antigen, adhesion glycoprotein, platelet and T cell activation antigen 1

Genomic Location:

Chr 18: 65681172-65775139

Description:

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocyt...

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This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Gallus gallus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTANTCA_UNKNOWN ,  CTTTGA_LEF1_Q2 ,  PBX1_01 ,  TGATTTRY_GFI1_01

Cytogenetic Map:

18q22.2

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