QuickView for CD28 (gene)

Gene Symbol:

CD28 Homo sapiens

Full name:

CD28 molecule

Synonyms:

Tp44, T-cell-specific surface glycoprotein CD28, CD28 antigen

Genomic Location:

Chr 2: 204279443-204310801

Description:

The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AML_Q6 ,  ACTGTGA_MIR27A_MIR27B ,  ATAGGAA_MIR202 ,  CTCTGGA_MIR520A_MIR525 ,  ATACTGT_MIR144 ,  RACCACAR_AML_Q6 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  COREBINDINGFACTOR_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-503 ,  Predicted Gene Targets for miR-31 ,  Predicted Gene Targets for miR-384

Cytogenetic Map:

2q33.2

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