QuickView for CD300a (gene)
- Gene Symbol:
- CD300A
Homo sapiens - Full name:
- CD300a molecule
- Synonyms:
- CLM-8, CMRF-35-H9, CMRF-35H, CMRF35-H, CMRF35-H9, CMRF35H, CMRF35H9, IGSF12, IRC1, IRC1/IRC2, IRC2, IRp60, CMRF35-like molecule 8, CD300 antigen-like family member A, CD300a antigen, CMRF35H leukocyte immunoglobulin-like receptor, NK inhibitory receptor, immunoglobulin superfamily member 12, inhibitory receptor protein 60, leukocyte membrane antigen
- Genomic Location:
- Chr 17: 69974117-69992528
- Description:
-
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
17q25.1
| Transcripts Names |
|---|
| NM_007261 |
| NM_001256841 |
| XM_005256990 |
| XM_006721656 |
| NM_001330456 |
| NM_001330457 |
| XM_005256991 |
GO Molecular Function
modified amino acid binding | lipid binding | phospholipid binding | phosphatidylethanolamine binding | anion binding | signaling receptor activity | ion binding | protein binding | phosphatidylserine binding
GO Biological Process
negative regulation of leukocyte activation | negative regulation of phosphorylation | negative regulation of intracellular transport | regulation of dephosphorylation | negative regulation of MAPK cascade | negative regulation of immune system process | exocytosis | regulation of B cell activation | neutrophil activation | regulation of cellular localization | regulation of localization | negative regulation of phagocytosis | establishment of localization | regulation of immune system process | positive regulation of phosphoprotein phosphatase activity | negative regulation of cellular process | negative regulation of kinase activity | negative regulation of leukocyte cell-cell adhesion | regulation of MAP kinase activity | regulation of phosphatase activity | negative regulation of eosinophil migration | negative regulation of B cell proliferation | negative regulation of membrane invagination | negative regulation of protein phosphorylation | regulation of phagocytosis, engulfment | positive regulation of phosphate metabolic process | positive regulation of dephosphorylation | cellular process | secretion | leukocyte degranulation | regulation of cell motility | localization | negative regulation of signaling | positive regulation of immune effector process | negative regulation of secretion | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | negative regulation of cellular metabolic process | regulation of T cell receptor signaling pathway | negative regulation of mast cell activation | negative regulation of cell motility | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | negative regulation of mononuclear cell proliferation | positive regulation of cellular protein metabolic process | regulation of mast cell degranulation | negative regulation of toll-like receptor signaling pathway | negative regulation of NK T cell activation | response to stimulus | neutrophil degranulation | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | negative regulation of cell adhesion | negative regulation of lymphocyte activation | leukocyte activation involved in immune response | negative regulation of protein kinase activity | regulation of activation of Janus kinase activity | regulation of cell proliferation | positive regulation of phosphatase activity | secretion by cell | negative regulation of transport | regulation of phagocytosis | negative regulation of metabolic process | negative regulation of neutrophil activation | regulation of cell adhesion | positive regulation of protein dephosphorylation | regulation of intracellular transport | regulation of MyD88-dependent toll-like receptor signaling pathway | regulation of signal transduction | negative regulation of secretion by cell | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of toll-like receptor signaling pathway | regulation of MAPK cascade | leukocyte mediated immunity | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | negative regulation of activation of Janus kinase activity | regulation of phosphorylation | regulation of T cell activation | positive regulation of cellular metabolic process | regulation of lymphocyte activation | regulation of mast cell activation | regulation of nitrogen compound metabolic process | negative regulation of T cell activation | regulation of cell migration | negative regulation of protein serine/threonine kinase activity | vesicle-mediated transport | regulation of cellular component movement | positive regulation of hydrolase activity | regulation of cellular protein metabolic process | negative regulation of immune response | regulated exocytosis | regulation of leukocyte migration | negative regulation of cell-cell adhesion | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | negative regulation of cell activation | cell activation involved in immune response | myeloid cell activation involved in immune response | regulation of protein metabolic process | neutrophil activation involved in immune response | negative regulation of MyD88-dependent toll-like receptor signaling pathway | regulation of protein phosphorylation | regulation of locomotion | negative regulation of MAP kinase activity | negative regulation of mast cell activation involved in immune response | negative regulation of B cell activation | positive regulation of molecular function | negative regulation of exocytosis | regulation of fibroblast proliferation | positive regulation of protein modification process | regulation of innate immune response | regulation of protein dephosphorylation | regulation of JAK-STAT cascade | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | regulation of exocytosis | negative regulation of endocytosis | negative regulation of leukocyte proliferation | regulation of vesicle-mediated transport | regulation of secretion | cell adhesion | immune response | negative regulation of eosinophil activation | negative regulation of cellular protein metabolic process | regulation of cell activation | negative regulation of cellular component movement | regulation of phosphate metabolic process | regulation of regulated secretory pathway | cell activation | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of endocytosis | negative regulation of peptidyl-tyrosine phosphorylation | negative regulation of fibroblast proliferation | negative regulation of leukocyte migration | regulation of phosphoprotein phosphatase activity | negative regulation of alpha-beta T cell activation | negative regulation of phagocytosis, engulfment | regulation of transport | regulation of B cell proliferation | negative regulation of cell proliferation | regulation of cell-cell adhesion | neutrophil mediated immunity | regulation of B cell receptor signaling pathway | positive regulation of metabolic process | negative regulation of lymphocyte proliferation | immune system process | negative regulation of B cell receptor signaling pathway | negative regulation of locomotion | regulation of cellular component organization | negative regulation of mast cell degranulation | signal transduction | regulation of signaling | regulation of phosphorus metabolic process
GO Cellular Component
secretory granule | integral component of membrane | organelle membrane | tertiary granule | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | secretory granule membrane | ficolin-1-rich granule membrane | secretory vesicle | endomembrane system | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | vesicle membrane | extracellular space | cell periphery | tertiary granule membrane | intracellular vesicle | intracellular | membrane | cytoplasmic vesicle membrane
