QuickView for CD300f (gene)
- Gene Symbol:
- CD300LF
Homo sapiens - Full name:
- CD300 molecule like family member f
- Synonyms:
- CD300f, CLM-1, CLM1, IREM-1, IREM1, IgSF13, LMIR3, NKIR, CMRF35-like molecule 1, CD300 antigen-like family member F, NK inhibitory receptor, immune receptor expressed on myeloid cells 1, immunoglobin superfamily member 13, immunoglobulin superfamily member 13, inhibitory receptor IREM1
- Genomic Location:
- Chr 17: 70202047-70220703
- Description:
-
This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
17q25.1
GO Molecular Function
ceramide binding | modified amino acid binding | lipid binding | signaling receptor binding | cytokine receptor binding | phospholipid binding | interleukin-4 receptor binding | anion binding | amide binding | sphingolipid binding | ion binding | protein binding | phosphatidylserine binding | growth factor receptor binding
GO Biological Process
positive regulation of immune response | negative regulation of leukocyte activation | negative regulation of immune system process | response to cytokine | positive regulation of cellular component organization | immune response-regulating signaling pathway | regulation of localization | negative regulation of phagocytosis | regulation of immune system process | negative regulation of cellular process | innate immune response-activating signal transduction | cellular process | toll-like receptor signaling pathway | interleukin-13-mediated signaling pathway | negative regulation of signaling | regulation of response to cytokine stimulus | negative regulation of mast cell activation | positive regulation of apoptotic cell clearance | regulation of immune response | regulation of cellular process | negative regulation of toll-like receptor signaling pathway | positive regulation of interleukin-4-mediated signaling pathway | response to stimulus | negative regulation of apoptotic cell clearance | positive regulation of innate immune response | positive regulation of immune system process | activation of innate immune response | immune response-activating signal transduction | negative regulation of transport | regulation of phagocytosis | regulation of MyD88-dependent toll-like receptor signaling pathway | positive regulation of response to cytokine stimulus | regulation of signal transduction | pattern recognition receptor signaling pathway | regulation of toll-like receptor signaling pathway | cellular response to interleukin-13 | regulation of mast cell activation | cytokine-mediated signaling pathway | cellular response to cytokine stimulus | TRIF-dependent toll-like receptor signaling pathway | cell communication | negative regulation of cell activation | positive regulation of signal transduction | negative regulation of MyD88-dependent toll-like receptor signaling pathway | regulation of cytokine-mediated signaling pathway | positive regulation of transport | regulation of apoptotic cell clearance | activation of immune response | response to organic substance | regulation of innate immune response | MyD88-independent toll-like receptor signaling pathway | cell surface receptor signaling pathway | negative regulation of endocytosis | regulation of vesicle-mediated transport | regulation of cell activation | positive regulation of phagocytosis | positive regulation of cytokine-mediated signaling pathway | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of endocytosis | regulation of transport | immune system process | cellular response to organic substance | positive regulation of endocytosis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | response to interleukin-13
GO Cellular Component
integral component of membrane | cell | intrinsic component of membrane | plasma membrane | cell periphery | membrane
