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QuickView for CD36L2 (gene)


Gene Symbol:
SCARB2 Homo sapiens Homo sapiens
Full name:
scavenger receptor class B member 2
Synonyms:
AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII, lysosome membrane protein 2, 85 kDa lysosomal membrane sialoglycoprotein, 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2, CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II), CD36 antigen-like 2, LIMP II, lysosome membrane protein II
Genomic Location:
Chr 4: 77298918-77354059
Description:
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impai...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 4
4q21.1


Transcripts Names
NM_005506
NM_001204255



GO Molecular Function

transmembrane signaling receptor activity | enzyme binding | signaling receptor activity | protein binding | scavenger receptor activity | virus receptor activity | cargo receptor activity

GO Biological Process

positive regulation of cellular component organization | regulation of neurogenesis | regulation of vacuole organization | regulation of cell development | phagocytosis, engulfment | protein localization to vacuole | establishment of localization | positive regulation of developmental process | cell differentiation | defense response | nervous system development | neurogenesis | regulation of organelle organization | generation of neurons | membrane organization | intracellular transport | cellular process | production of molecular mediator involved in inflammatory response | localization | protein transport | macromolecule localization | regulation of neuron projection development | establishment of localization in cell | regulation of cell differentiation | interspecies interaction between organisms | regulation of cellular process | cellular component organization | entry into host cell | cellular lipid metabolic process | viral life cycle | response to stimulus | lysosomal transport | monocarboxylic acid metabolic process | protein targeting to lysosome | response to stress | intracellular protein transport | vacuolar transport | cellular localization | protein targeting to vacuole | regulation of membrane potential | system development | regulation of signal transduction | positive regulation of neuron projection development | multicellular organism development | regulation of glucosylceramidase activity | regulation of catalytic activity | lipid metabolic process | protein localization to lysosome | regulation of neuron differentiation | viral entry into host cell | organic substance transport | small molecule metabolic process | positive regulation of cell projection organization | peptide transport | vesicle-mediated transport | protein localization to organelle | positive regulation of cell differentiation | regulation of lysosome organization | cell communication | inflammatory response | viral process | carboxylic acid metabolic process | scavenger receptor activity | regulation of lipopolysaccharide-mediated signaling pathway | import into cell | establishment of protein localization to organelle | anatomical structure development | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | cellular protein localization | membrane invagination | amide transport | endocytosis | organic substance metabolic process | virus receptor activity | regulation of endosome organization | establishment of protein localization to vacuole | fatty acid metabolic process | establishment of protein localization | regulation of cell communication | action potential | signaling | protein localization | organic acid metabolic process | cellular macromolecule localization | regulation of nervous system development | regulation of developmental process | receptor-mediated endocytosis | developmental process | positive regulation of neuron differentiation | protein targeting | cargo receptor activity | regulation of cell projection organization | cellular metabolic process | phagocytosis | regulation of cellular component organization | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | late endosome | clathrin-coated vesicle membrane | adherens junction | organelle membrane | clathrin-coated vesicle | focal adhesion | cytoplasmic vesicle | cell | late endosome membrane | vacuolar lumen | intrinsic component of membrane | cytoplasm | cell-substrate junction | intracellular organelle | endoplasmic reticulum | endosome membrane | Golgi apparatus | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | vacuole | vesicle | extracellular exosome | lytic vacuole | Golgi membrane | endosome | extracellular region | coated vesicle membrane | membrane-bounded organelle | extracellular vesicle | organelle | vesicle membrane | lysosome | extracellular space | cell periphery | membrane-enclosed lumen | cell-substrate adherens junction | lysosomal lumen | intracellular vesicle | cell surface | intracellular | cell junction | lysosomal membrane | membrane | cytoplasmic vesicle membrane | vacuolar membrane | coated vesicle