QuickView for CD39 (gene)
- Gene Symbol:
- ENTPD1
Homo sapiens - Full name:
- ectonucleoside triphosphate diphosphohydrolase 1
- Synonyms:
- ATPDase, CD39, NTPDase-1, SPG64, ectonucleoside triphosphate diphosphohydrolase 1, CD39 antigen, ecto-ATP diphosphohydrolase 1, ecto-ATPDase 1, ecto-ATPase 1, ecto-apyrase, lymphoid cell activation antigen
- Genomic Location:
- Chr 10: 97461526-97627013
- Description:
-
The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Danio rerio , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
MAZR_01 , MZF1_01 , SRY_01 , AML1_01 , WTGAAAT_UNKNOWN , GGGAGGRR_MAZ_Q6 , AML1_Q6 , OCT1_02 , TAATTA_CHX10_01 , TTGTTT_FOXO4_01
- Cytogenetic Map:
-
10q24.1
GO Molecular Function
dCTP phosphohydrolase activity | 8-oxo-dGTP phosphohydrolase activity | ribonucleotide binding | nucleotide binding | hydrolase activity | GTP phosphohydrolase activity | carbohydrate derivative binding | pyrophosphatase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | purine nucleotide binding | ion binding | organic cyclic compound binding | dGTP phosphohydrolase activity | purine ribonucleoside triphosphate binding | protein binding | dATP phosphohydrolase activity | dUTP phosphohydrolase activity | nucleoside-diphosphatase activity | hydrolase activity, acting on acid anhydrides | dTTP phosphohydrolase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding
GO Biological Process
cellular process | organic substance catabolic process | hemostasis | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | response to stress | cellular nitrogen compound metabolic process | nucleobase-containing compound catabolic process | blood coagulation | nitrogen compound metabolic process | wound healing | nucleobase-containing small molecule catabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | aromatic compound catabolic process | coagulation | response to wounding | metabolic process | regulation of body fluid levels | cell adhesion | nucleobase-containing compound metabolic process | organic substance metabolic process | heterocycle metabolic process | cellular metabolic process | multicellular organismal process
GO Cellular Component
integral component of membrane | cell | intrinsic component of membrane | plasma membrane | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | membrane | intrinsic component of plasma membrane
