Correlation Engine 2.0
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QuickView for CD3H (gene)


Gene Symbol:
CD247 Homo sapiens Homo sapiens
Full name:
CD247 molecule
Synonyms:
CD3-ZETA, CD3H, CD3Q, CD3Z, IMD25, T3Z, TCRZ, T-cell surface glycoprotein CD3 zeta chain, CD247 antigen, zeta subunit, CD3Z antigen, zeta polypeptide (TiT3 complex), CD3zeta chain, T-cell antigen receptor complex, zeta subunit of CD3, T-cell receptor T3 zeta chain, TCR zeta chain
Genomic Location:
Chr 1: 165666505-165754450
Description:
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expre...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1q24.2





GO Molecular Function

kinase binding | protein kinase binding | transmembrane signaling receptor activity | enzyme binding | signaling receptor activity | identical protein binding | protein tyrosine kinase binding | protein binding | protein homodimerization activity | protein dimerization activity

GO Biological Process

positive regulation of immune response | protein homooligomerization | adaptive immune response | immune response-regulating signaling pathway | regulation of cellular localization | regulation of localization | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | immune response-activating cell surface receptor signaling pathway | T cell receptor signaling pathway | cellular process | Fc-gamma receptor signaling pathway involved in phagocytosis | localization | interspecies interaction between organisms | regulation of immune response | regulation of cellular process | cellular component organization | response to stimulus | regulation of cellular protein localization | positive regulation of immune system process | positive regulation of cellular protein localization | protein homotrimerization | interleukin-2 production | immune response-activating signal transduction | cellular component assembly | protein complex oligomerization | regulation of protein localization to cell surface | Fc-gamma receptor signaling pathway | positive regulation of protein localization to cell surface | vesicle-mediated transport | protein homotetramerization | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | protein tetramerization | cell communication | protein trimerization | viral process | cytokine production | protein-containing complex assembly | activation of immune response | import into cell | cell surface receptor signaling pathway | regulation of defense response to virus by virus | endocytosis | immune response | antigen receptor-mediated signaling pathway | signaling | Fc receptor signaling pathway | Fc receptor mediated stimulatory signaling pathway | immune system process | regulation of protein localization | phagocytosis | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | T cell receptor complex | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | receptor complex | protein-containing complex | alpha-beta T cell receptor complex | plasma membrane | cell periphery | intracellular | membrane