QuickView for CD70 (gene)

Gene Symbol:

CD70 Homo sapiens

Full name:

CD70 molecule

Synonyms:

CD27-L, CD27L, CD27LG, TNFSF7, TNLG8A, CD70 antigen, CD27 ligand, Ki-24 antigen, surface antigen CD70, tumor necrosis factor ligand 8A, tumor necrosis factor ligand superfamily member 7

Genomic Location:

Chr 19: 6536850-6542163

Description:

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T...

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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFKAPPAB_01 ,  NFKAPPAB65_01 ,  CREL_01 ,  NFKB_Q6_01 ,  NFKB_Q6 ,  NFKB_C ,  GGGNNTTTCC_NFKB_Q6_01

Cytogenetic Map:

19p13.3

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