QuickView for CD88 (gene)
- Gene Symbol:
- C5AR1
Homo sapiens - Full name:
- complement C5a receptor 1
- Synonyms:
- C5A, C5AR, C5R1, CD88, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a-R, complement component 5 receptor 1, complement component 5a receptor 1
- Genomic Location:
- Chr 19: 52504944-52517167
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
19q13.32
GO Molecular Function
transmembrane signaling receptor activity | complement binding | G-protein coupled receptor activity | signaling receptor activity | protein binding | complement receptor activity | opsonin receptor activity | complement component C5a binding | complement component C5a receptor activity
GO Biological Process
positive regulation of immune response | RNA metabolic process | transcription by RNA polymerase II | regulation of leukocyte chemotaxis | regulation of ERK1 and ERK2 cascade | brain development | positive regulation of locomotion | exocytosis | cell motility | immune response-regulating signaling pathway | neutrophil activation | response to lipopolysaccharide | regulation of localization | regulation of programmed cell death | defense response to other organism | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | immune response-activating cell surface receptor signaling pathway | positive regulation of epithelial cell proliferation | defense response | nervous system development | cellular chemical homeostasis | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | regulation of neuron death | cellular process | secretion | positive regulation of macrophage migration | leukocyte degranulation | regulation of cell motility | localization | cellular homeostasis | positive regulation of protein kinase activity | regulation of chemotaxis | negative regulation of apoptotic process | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | granulocyte chemotaxis | activation of phospholipase C activity | regeneration | regulation of angiogenesis | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | positive regulation of neutrophil migration | regulation of cytosolic calcium ion concentration | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | calcium ion homeostasis | regulation of neutrophil chemotaxis | head development | G-protein coupled receptor activity | regulation of vasculature development | response to stimulus | neutrophil degranulation | neutrophil chemotaxis | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | leukocyte activation involved in immune response | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | complement component C5a signaling pathway | regulation of humoral immune response | programmed cell death | positive regulation of vascular endothelial growth factor production | secretion by cell | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | positive regulation of lipase activity | immune response-activating signal transduction | G-protein coupled receptor signaling pathway | positive regulation of protein serine/threonine kinase activity | regulation of protein processing | mRNA metabolic process | cellular biosynthetic process | cell chemotaxis | activation of protein kinase activity | metal ion homeostasis | leukocyte migration | locomotion | positive regulation of phospholipase C activity | response to nitrogen compound | negative regulation of neuron apoptotic process | apoptotic process | response to external biotic stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | cell migration | regulation of MAPK cascade | leukocyte mediated immunity | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of granulocyte chemotaxis | regulation of phosphorylation | mRNA transcription by RNA polymerase II | regulation of acute inflammatory response | regulation of gene expression | positive regulation of chemotaxis | response to lipid | nervous system process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | response to peptidoglycan | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of cell migration | positive regulation of intracellular signal transduction | vesicle-mediated transport | regulation of cellular component movement | positive regulation of hydrolase activity | positive regulation of cell migration | cell proliferation | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | hindbrain development | regulated exocytosis | regulation of phospholipase activity | regulation of complement activation | positive regulation of macrophage chemotaxis | cation homeostasis | regulation of leukocyte migration | response to bacterium | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of neuron apoptotic process | positive regulation of leukocyte chemotaxis | inflammatory response | cell activation involved in immune response | myeloid cell activation involved in immune response | regulation of protein metabolic process | positive regulation of signal transduction | neutrophil activation involved in immune response | leukocyte chemotaxis | cell proliferation in hindbrain | cellular calcium ion homeostasis | defense response to bacterium | homeostatic process | positive regulation of cell proliferation | mRNA transcription | regulation of protein phosphorylation | regulation of locomotion | complement receptor mediated signaling pathway | regulation of phospholipase C activity | positive regulation of molecular function | activation of MAPK activity | activation of immune response | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of neutrophil migration | negative regulation of programmed cell death | positive regulation of neutrophil chemotaxis | chemical homeostasis | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | cell death | animal organ development | gene expression | positive regulation of leukocyte migration | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | ion homeostasis | neural precursor cell proliferation | regulation of phosphate metabolic process | phospholipase C-activating G-protein coupled receptor signaling pathway | transcription, DNA-templated | positive regulation of cytokine production | positive regulation of phospholipase activity | cell activation | positive regulation of MAPK cascade | sensory perception | defense response to Gram-positive bacterium | regulation of cell communication | complement receptor activity | signaling | sensory perception of chemical stimulus | regulation of epithelial cell proliferation | positive regulation of phosphorylation | regulation of cytokine production | cellular macromolecule biosynthetic process | positive regulation of MAP kinase activity | response to biotic stimulus | regulation of developmental process | developmental process | cellular defense response | neutrophil mediated immunity | response to organonitrogen compound | positive regulation of granulocyte chemotaxis | cellular metal ion homeostasis | heterocycle metabolic process | regulation of vascular endothelial growth factor production | regulation of macrophage chemotaxis | central nervous system development | positive regulation of metabolic process | immune system process | cellular metabolic process | complement component C5a receptor activity | regulation of cell death | positive regulation of cell motility | negative regulation of cell death | neutrophil migration | regulation of inflammatory response | chemotaxis | divalent inorganic cation homeostasis | positive regulation of angiogenesis | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | animal organ regeneration | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
secretory granule | integral component of membrane | organelle membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | secretory granule membrane | apical part of cell | secretory vesicle | endomembrane system | plasma membrane | vesicle | integral component of plasma membrane | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | basolateral plasma membrane | intracellular vesicle | cell surface | intracellular | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane
