QuickView for CDAR1 (gene)

Gene Symbol:

APOBEC1 Homo sapiens

Full name:

apolipoprotein B mRNA editing enzyme catalytic subunit 1

Synonyms:

APOBEC-1, BEDP, CDAR1, HEPR, C->U-editing enzyme APOBEC-1, apolipoprotein B mRNA editing enzyme complex-1, apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1, apolipoprotein B mRNA-editing enzyme 1, mRNA(cytosine(6666)) deaminase 1

Genomic Location:

Chr 12: 7693263-7709769

Description:

This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcr...

View Full Description

This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGANTCA_AP1_C ,  AP1_Q6 ,  CAGGTG_E12_Q6 ,  AP1_01 ,  CTCAGGG_MIR125B_MIR125A ,  AP1FJ_Q2 ,  BACH2_01 ,  AP1_Q4 ,  BACH1_01 ,  AP1_Q2

Cytogenetic Map:

12p13.31

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