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QuickView for CDC25A2 (gene)


Gene Symbol:
CDC25A Homo sapiens Homo sapiens
Full name:
cell division cycle 25A
Synonyms:
CDC25A2, M-phase inducer phosphatase 1, CDC25 isoform A1-CAG, CDC25A2-CAG isoform, dual specificity phosphatase CDC25A
Genomic Location:
Chr 3: 48173672-48204805
Description:
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through c...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 3
3p21.31





GO Molecular Function

kinase binding | protein kinase binding | enzyme binding | phosphatase activity | hydrolase activity | protein tyrosine phosphatase activity | catalytic activity | chaperone binding | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | protein binding | phosphoric ester hydrolase activity

GO Biological Process

protein modification by small protein removal | response to radiation | regulation of cell cycle process | protein dephosphorylation | proteolysis | regulation of meiotic cell cycle | positive regulation of G2/M transition of mitotic cell cycle | positive regulation of meiotic cell cycle phase transition | cellular process | regulation of cell cycle | regulation of cellular process | regulation of metabolic process | positive regulation of cell cycle phase transition | regulation of G2/M transition of mitotic cell cycle | protein deubiquitination | phosphatase activity | response to UV | response to stimulus | regulation of mitotic cell cycle phase transition | cellular response to light stimulus | regulation of cell cycle phase transition | cell cycle G1/S phase transition | positive regulation of meiotic cell cycle | protein modification process | macromolecule modification | protein tyrosine phosphatase activity | regulation of cell cycle G2/M phase transition | response to light stimulus | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | phosphorus metabolic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | positive regulation of cell cycle | positive regulation of mitotic cell cycle | cell cycle | cellular response to radiation | phosphoprotein phosphatase activity | regulation of nitrogen compound metabolic process | positive regulation of cell cycle G2/M phase transition | cell proliferation | positive regulation of G2/MI transition of meiotic cell cycle | cell division | regulation of cellular protein metabolic process | G2/M transition of mitotic cell cycle | mitotic cell cycle phase transition | phosphate-containing compound metabolic process | cellular response to UV | regulation of meiotic cell cycle phase transition | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | cell cycle G2/M phase transition | G1/S transition of mitotic cell cycle | regulation of protein phosphorylation | regulation of mitotic cell cycle | protein metabolic process | regulation of kinase activity | positive regulation of mitotic cell cycle phase transition | mitotic cell cycle | metabolic process | organic substance metabolic process | protein modification by small protein conjugation or removal | regulation of phosphate metabolic process | dephosphorylation | cellular protein metabolic process | positive regulation of cell cycle process | cellular protein modification process | peptidyl-tyrosine dephosphorylation | cell cycle phase transition | cellular metabolic process | macromolecule metabolic process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular