QuickView for CDC34 (gene)
- Gene Symbol:
- CDC34
Homo sapiens - Full name:
- cell division cycle 34
- Synonyms:
- E2-CDC34, UBC3, UBCH3, UBE2R1, ubiquitin-conjugating enzyme E2 R1, (E3-independent) E2 ubiquitin-conjugating enzyme R1, E2 ubiquitin-conjugating enzyme R1, cell division cycle 34 homolog, ubiquitin carrier protein, ubiquitin-conjugating enzyme E2-32 KDA complementing, ubiquitin-conjugating enzyme E2-CDC34, ubiquitin-protein ligase R1
- Genomic Location:
- Chr 19: 482733-493087
- Description:
-
The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of ...
- Orthologs:
- Mus musculus , Rattus norvegicus , Gallus gallus , Danio rerio , Canis lupus familiaris , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
19p13.3
GO Molecular Function
ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | ubiquitin-like protein transferase activity | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | ubiquitin-protein transferase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heterocyclic compound binding | ubiquitin conjugating enzyme activity | small molecule binding
GO Biological Process
response to cytokine | positive regulation of cellular component organization | positive regulation of apoptotic process | proteolysis | regulation of programmed cell death | negative regulation of cellular process | regulation of neuron death | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | negative regulation of signaling | response to growth factor | regulation of cellular process | regulation of apoptotic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | DNA-dependent DNA replication | DNA replication initiation | response to stimulus | response to interferon-beta | cellular protein catabolic process | cellular nitrogen compound metabolic process | proteasomal protein catabolic process | cell cycle G1/S phase transition | protein modification process | cellular biosynthetic process | macromolecule modification | nitrogen compound metabolic process | regulation of signal transduction | cell cycle | protein catabolic process | protein modification by small protein conjugation | cellular response to cytokine stimulus | biosynthetic process | positive regulation of neuron death | mitotic cell cycle phase transition | regulation of neuron apoptotic process | regulation of cAMP-mediated signaling | G1/S transition of mitotic cell cycle | proteasome-mediated ubiquitin-dependent protein catabolic process | protein polyubiquitination | protein metabolic process | response to organic substance | protein ubiquitination | DNA metabolic process | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | cellular macromolecule catabolic process | positive regulation of neuron apoptotic process | mitotic cell cycle | metabolic process | ubiquitin-protein transferase activity | positive regulation of cell death | nucleobase-containing compound metabolic process | positive regulation of cellular component biogenesis | organic substance metabolic process | positive regulation of programmed cell death | protein modification by small protein conjugation or removal | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of signal transduction | cellular protein metabolic process | cellular macromolecule biosynthetic process | cellular response to interferon-beta | negative regulation of cAMP-mediated signaling | cellular protein modification process | regulation of inclusion body assembly | positive regulation of inclusion body assembly | cell cycle phase transition | heterocycle metabolic process | protein K48-linked ubiquitination | cellular metabolic process | cellular response to organic substance | regulation of cell death | modification-dependent protein catabolic process | DNA replication | regulation of cellular component organization | ubiquitin conjugating enzyme activity | regulation of signaling | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | nucleoplasm | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
