QuickView for CDC42EP2;jsessionid=A8884CCDB75E8317A825CD3635FA524A (gene)

Gene Symbol:

CDC42EP2 Homo sapiens

Full name:

CDC42 effector protein 2

Synonyms:

BORG1, CEP2, cdc42 effector protein 2, CDC42 effector protein (Rho GTPase binding) 2, CRIB-containing BOGR1 protein, binder of Rho GTPases 1

Genomic Location:

Chr 11: 64838907-64846476

Description:

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regula...

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CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA3_01 ,  LYF1_01 ,  CTAWWWATA_RSRFC4_Q2 ,  GGGAGGRR_MAZ_Q6 ,  RP58_01 ,  TATA_C ,  GGGCGGR_SP1_Q6 ,  HIF1_Q5 ,  GATA1_02 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-15

Cytogenetic Map:

11q13.1

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