QuickView for CDC42GAP (gene)

Gene Symbol:

ARHGAP1 Homo sapiens

Full name:

Rho GTPase activating protein 1

Synonyms:

CDC42GAP, RHOGAP, RHOGAP1, p50rhoGAP, rho GTPase-activating protein 1, CDC42 GTPase-activating protein, GTPase-activating protein rhoGAP, GTPase-activating protein rhoOGAP, GTPase-activating protein, Rho, 1, rho-related small GTPase protein activator, rho-type GTPase-activating protein 1

Genomic Location:

Chr 11: 46655206-46678696

Description:

This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members.

This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CACTGCC_MIR34A_MIR34C_MIR449 ,  TTTGCAC_MIR19A_MIR19B ,  CIZ_01 ,  TEL2_Q6 ,  TTGCACT_MIR130A_MIR301_MIR130B ,  ACCAATC_MIR509 ,  GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D ,  GGGCGGR_SP1_Q6 ,  ACTGCCT_MIR34B ,  MGGAAGTG_GABP_B ,  RNGTGGGC_UNKNOWN ,  CETS1P54_01 ,  ELK1_01 ,  SCGGAAGY_ELK1_02 ,  NRF2_01 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  TGACAGNY_MEIS1_01 ,  ELK1_02 ,  P300_01 ,  MZF1_02 ,  SRF_C

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-20 ,  Predicted Gene Targets for miR-34 ,  Predicted Gene Targets for miR-34b

Cytogenetic Map:

11p11.2

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