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QuickView for CDH1 (gene)


Gene Symbol:
CDH1 Homo sapiens Homo sapiens
Full name:
cadherin 1
Synonyms:
Arc-1, BCDS1, CD324, CDHE, ECAD, LCAM, UVO, cadherin-1, CAM 120/80, E-cadherin 1, cadherin 1, E-cadherin (epithelial), cadherin 1, type 1, E-cadherin (epithelial), calcium-dependent adhesion protein, epithelial, cell-CAM 120/80, epithelial cadherin, uvomorulin
Genomic Location:
Chr 16: 67328696-67426945
Description:
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 16
16q22.1





GO Molecular Function

beta-catenin binding | cadherin binding | cation binding | cytoskeletal protein binding | gamma-catenin binding | identical protein binding | ion binding | ankyrin binding | cell adhesion molecule binding | protein binding | protein homodimerization activity | GTPase activating protein binding | protein dimerization activity | calcium ion binding | metal ion binding

GO Biological Process

brain development | positive regulation of macromolecule biosynthetic process | regulation of intracellular protein transport | extracellular structure organization | protein localization to cell periphery | regulation of cellular localization | regulation of localization | cellular response to indole-3-methanol | negative regulation of cellular process | cell-cell adhesion mediated by cadherin | response to metal ion | regulation of protein import | cell differentiation | nervous system development | response to drug | neurogenesis | generation of neurons | positive regulation of cellular biosynthetic process | cellular process | localization | neuron development | synapse assembly | macromolecule localization | positive regulation of nitrogen compound metabolic process | diencephalon development | response to inorganic substance | interspecies interaction between organisms | cell junction assembly | regulation of cellular process | regulation of metabolic process | pituitary gland development | cellular response to organonitrogen compound | cellular component organization | entry into host cell | cellular response to metal ion | head development | response to stimulus | cellular response to lithium ion | regulation of cellular protein localization | negative regulation of cell adhesion | positive regulation of cellular protein localization | cellular response to inorganic substance | cellular localization | response to alcohol | extracellular matrix organization | cellular response to organic cyclic compound | regulation of protein transport | positive regulation of RNA biosynthetic process | cellular component assembly | regulation of peptide transport | regulation of cell adhesion | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules | regulation of intracellular transport | regulation of nucleic acid-templated transcription | response to nitrogen compound | system development | adherens junction organization | multicellular organism development | protein localization to plasma membrane | regulation of gene expression | protein localization to membrane | entry of bacterium into host cell | positive regulation of intracellular protein transport | positive regulation of cellular metabolic process | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | response to lithium ion | synapse organization | positive regulation of protein localization to nucleus | response to toxic substance | endocrine system development | cellular response to drug | negative regulation of cell-cell adhesion | regulation of cellular metabolic process | positive regulation of establishment of protein localization | regulation of RNA metabolic process | positive regulation of transport | regulation of nucleocytoplasmic transport | neuron differentiation | regulation of establishment of protein localization | response to organic substance | gland development | regulation of protein import into nucleus | response to antineoplastic agent | anatomical structure development | cell projection organization | cell-cell junction assembly | regulation of RNA biosynthetic process | cellular protein localization | cell adhesion | neuron projection development | animal organ development | forebrain development | cell-cell adhesion | positive regulation of intracellular transport | positive regulation of protein transport | regulation of transcription, DNA-templated | response to organic cyclic compound | response to indole-3-methanol | cell development | protein localization | cellular macromolecule localization | positive regulation of protein import into nucleus | developmental process | positive regulation of protein import | regulation of transport | positive regulation of transcription, DNA-templated | regulation of cell-cell adhesion | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | central nervous system development | cell-cell adhesion via plasma-membrane adhesion molecules | positive regulation of metabolic process | cellular response to organic substance | regulation of protein localization | positive regulation of nucleocytoplasmic transport | positive regulation of gene expression | homophilic cell adhesion via plasma membrane adhesion molecules | multicellular organismal process | cell-cell junction organization

GO Cellular Component

integral component of membrane | cytoplasmic side of plasma membrane | intracellular membrane-bounded organelle | extrinsic component of membrane | catenin complex | adherens junction | cytoplasmic vesicle | cell | cytoplasmic side of membrane | plasma membrane protein complex | extrinsic component of plasma membrane | intrinsic component of membrane | lamellipodium | cytoplasm | cortical cytoskeleton | intracellular organelle | actin cytoskeleton | membrane microdomain | cell-cell adherens junction | cell-cell junction | Golgi apparatus | protein-containing complex | cell projection | endomembrane system | plasma membrane | cell leading edge | membrane raft | vesicle | perinuclear region of cytoplasm | extracellular exosome | cytoplasmic region | cortical actin cytoskeleton | endosome | extracellular region | cell cortex | membrane-bounded organelle | extracellular vesicle | apical junction complex | organelle | flotillin complex | extracellular space | cell periphery | trans-Golgi network | plasma membrane raft | intracellular vesicle | cell surface | cytoskeleton | intracellular | cell junction | caveola | lateral plasma membrane | membrane