QuickView for CDH6 (gene)
- Gene Symbol:
- CDH6
Homo sapiens - Full name:
- cadherin 6
- Synonyms:
- CAD6, KCAD, cadherin-6, cadherin 6, type 2, K-cadherin (fetal kidney)
- Genomic Location:
- Chr 5: 31229553-31360994
- Description:
-
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expres...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
5p13.3
GO Molecular Function
cadherin binding | cation binding | cytoskeletal protein binding | identical protein binding | ion binding | cell adhesion molecule binding | protein binding | protein homodimerization activity | protein dimerization activity | calcium ion binding | metal ion binding
GO Biological Process
Notch signaling pathway | cell-cell adhesion mediated by cadherin | cellular process | cell junction assembly | regulation of cellular process | cellular component organization | response to stimulus | cellular component assembly | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules | adherens junction organization | cell communication | cell surface receptor signaling pathway | cell-cell junction assembly | cell adhesion | cell-cell adhesion | signaling | cell-cell adhesion via plasma-membrane adhesion molecules | signal transduction | homophilic cell adhesion via plasma membrane adhesion molecules | cell-cell junction organization
GO Cellular Component
integral component of membrane | extrinsic component of membrane | catenin complex | adherens junction | cell | plasma membrane protein complex | extrinsic component of plasma membrane | intrinsic component of membrane | cell-cell adherens junction | cell-cell junction | protein-containing complex | plasma membrane | cell periphery | cell surface | cell junction | membrane
