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QuickView for CDK12 (gene)


Gene Symbol:
CDK12 Homo sapiens Homo sapiens
Full name:
cyclin dependent kinase 12
Synonyms:
CRK7, CRKR, CRKRS, cyclin-dependent kinase 12, CDC2-related protein kinase 7, Cdc2-related kinase, arginine/serine-rich, cell division cycle 2-related protein kinase 7, cell division protein kinase 12
Genomic Location:
Chr 17: 34871265-34944326
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 17
17q12





GO Molecular Function

kinase binding | transcription regulatory region DNA binding | cyclin binding | protein kinase binding | enzyme binding | nucleic acid binding | ribonucleotide binding | nucleotide binding | cyclin-dependent protein kinase activity | carbohydrate derivative binding | protein serine/threonine kinase activity | RNA polymerase II CTD heptapeptide repeat kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | DNA binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transcription factor binding | cyclin-dependent protein serine/threonine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | positive regulation of macromolecule biosynthetic process | RNA processing | negative regulation of cellular process | regulation of MAP kinase activity | positive regulation of cellular biosynthetic process | cellular process | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cyclin-dependent protein kinase activity | RNA splicing | cellular nitrogen compound biosynthetic process | protein serine/threonine kinase activity | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | protein modification process | mRNA metabolic process | RNA polymerase II CTD heptapeptide repeat kinase activity | cellular biosynthetic process | macromolecule modification | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of signal transduction | regulation of MAPK cascade | phosphorus metabolic process | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of gene expression | positive regulation of cellular metabolic process | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | phosphorylation of RNA polymerase II C-terminal domain | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | regulation of transcription elongation from RNA polymerase II promoter | phosphorylation | transcription elongation from RNA polymerase II promoter | protein phosphorylation | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of RNA metabolic process | regulation of stem cell differentiation | protein metabolic process | regulation of kinase activity | cyclin-dependent protein serine/threonine kinase activity | regulation of intracellular signal transduction | metabolic process | regulation of RNA splicing | positive regulation of transcription elongation from RNA polymerase II promoter | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | gene expression | negative regulation of stem cell differentiation | regulation of phosphate metabolic process | regulation of DNA-templated transcription, elongation | transcription, DNA-templated | regulation of cell communication | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of developmental process | kinase activity | positive regulation of DNA-templated transcription, elongation | cellular protein modification process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | mRNA processing | negative regulation of cell differentiation | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | DNA-templated transcription, elongation | regulation of phosphorus metabolic process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | catalytic complex | fibrillar center | transcription elongation factor complex | protein kinase complex | cell | nuclear lumen | cyclin/CDK positive transcription elongation factor complex | nucleolus | intracellular organelle | nuclear body | carboxy-terminal domain protein kinase complex | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | nuclear speck | nuclear cyclin-dependent protein kinase holoenzyme complex | transferase complex | cyclin K-CDK12 complex | serine/threonine protein kinase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cyclin-dependent protein kinase holoenzyme complex | nuclear chromatin | intracellular