QuickView for CDK5RAP2;jsessionid=331510596288DE07F0CBCA8037DDD95D (gene)

Gene Symbol:

CDK5RAP2 Homo sapiens

Full name:

CDK5 regulatory subunit associated protein 2

Synonyms:

C48, Cep215, MCPH3, CDK5 regulatory subunit-associated protein 2, CDK5 activator-binding protein C48, centrosomal protein 215 kDa, centrosomin

Genomic Location:

Chr 9: 122190968-122382258

Description:

This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative...

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This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris ,  Gallus gallus

External Links:

Entrez Gene

Cytogenetic Map:

9q33.2

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