QuickView for CDSN (gene)

Gene Symbol:

CDSN Homo sapiens

Full name:

corneodesmosin

Synonyms:

HTSS, HTSS1, HYPT2, PSS, PSS1, S, corneodesmosin, differentiated keratinocyte S protein

Genomic Location:

Chr 6: 31190849-31196202

Description:

This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis...

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This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis and peeling skin syndrome. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.

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Orthologs:

Mus musculus ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Cytogenetic Map:

6p21.33

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