QuickView for CDX-3 (gene)

Gene Symbol:

CDX2 Homo sapiens

Full name:

caudal type homeobox 2

Synonyms:

CDX-3, CDX2/AS, CDX3, homeobox protein CDX-2, caudal type homeobox transcription factor 2, caudal-type homeobox protein 2, homeobox protein miniCDX2

Genomic Location:

Chr 13: 27434278-27441317

Description:

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal ...

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This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  OCT1_05 ,  OCT1_B ,  TTANTCA_UNKNOWN ,  OCT1_01 ,  HOXA4_Q2 ,  OCT_Q6 ,  YNTTTNNNANGCARM_UNKNOWN ,  CTTTGA_LEF1_Q2 ,  TTF1_Q6 ,  GGTGAAG_MIR412 ,  OCT1_Q5_01 ,  HNF4_01 ,  TATAAA_TATA_01 ,  OCT1_Q6 ,  GTGACGY_E4F1_Q6 ,  MGGAAGTG_GABP_B ,  GFI1_01 ,  NCX_01 ,  EN1_01 ,  OCT1_02 ,  GGCAGCT_MIR22 ,  FREAC2_01 ,  ATF1_Q6 ,  SCGGAAGY_ELK1_02 ,  RGAGGAARY_PU1_Q6 ,  CTGAGCC_MIR24 ,  TGATTTRY_GFI1_01 ,  PPAR_DR1_Q2 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-204 ,  Predicted Gene Targets for miR-22 ,  Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-542-3p

Cytogenetic Map:

13q12.2

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