QuickView for CEBPE (gene)

Gene Symbol:

CEBPE Homo sapiens

Full name:

CCAAT/enhancer binding protein epsilon

Synonyms:

C/EBP-epsilon, CRP1, CCAAT/enhancer-binding protein epsilon, CCAAT/enhancer binding protein (C/EBP), epsilon, c/EBP epsilon

Genomic Location:

Chr 14: 22656355-22658314

Description:

The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this g...

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The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SP1_01 ,  PU1_Q6 ,  TTANTCA_UNKNOWN ,  RYTTCCTG_ETS2_B ,  GGGAGGRR_MAZ_Q6 ,  CAGGTG_E12_Q6 ,  GGGCGGR_SP1_Q6 ,  RGAGGAARY_PU1_Q6 ,  ELF1_Q6

Cytogenetic Map:

14q11.2

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