QuickView for CERT (gene)

Gene Symbol:

COL4A3BP Homo sapiens

Full name:

collagen type IV alpha 3 binding protein

Synonyms:

CERT, CERTL, GPBP, MRD34, STARD11, collagen type IV alpha-3-binding protein, StAR-related lipid transfer (START) domain containing 11, ceramide transfer protein, ceramide transporter, collagen, type IV, alpha 3 (Goodpasture antigen) binding protein, hCERT, lipid-transfer protein CERTL

Genomic Location:

Chr 5: 74710821-74843196

Description:

This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular trans...

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This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YTCCCRNNAGGY_UNKNOWN ,  NFMUE1_Q6 ,  HP1SITEFACTOR_Q6 ,  STAT3_02 ,  TCCCRNNRTGC_UNKNOWN ,  STAT5B_01 ,  CAGGTG_E12_Q6 ,  RRAGTTGT_UNKNOWN ,  AAGWWRNYGGC_UNKNOWN ,  ACTAYRNNNCCCR_UNKNOWN ,  ACTWSNACTNY_UNKNOWN ,  STAT_01 ,  RNGTGGGC_UNKNOWN ,  MTF1_Q4 ,  YY1_02 ,  IK2_01 ,  TTCYNRGAA_STAT5B_01 ,  WCAANNNYCAG_UNKNOWN ,  STAT5A_01 ,  OLF1_01

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Cytogenetic Map:

5q13.3

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