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QuickView for CES1 (gene)


Gene Symbol:
CES1 Homo sapiens Homo sapiens
Full name:
carboxylesterase 1
Synonyms:
ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1, liver carboxylesterase 1, acyl coenzyme A:cholesterol acyltransferase, brain carboxylesterase hBr1, carboxylesterase 1 (monocyte/macrophage serine esterase 1), carboxylesterase 2 (liver), cholesteryl ester hydrolase, cocaine carboxylesterase, egasyn, human monocyte/macrophage serine esterase 1, methylumbelliferyl-acetate deacetylase 1, monocyte/macrophage serine esterase, retinyl ester hydrolase, serine esterase 1, triacylglycerol hydrolase
Genomic Location:
Chr 16: 54394264-54424576
Description:
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus
External Links:
Entrez Gene
Cytogenetic Map:
chr 16
16q12.2





GO Molecular Function

carboxylic ester hydrolase activity | sterol esterase activity | hydrolase activity | catalytic activity | hydrolase activity, acting on ester bonds | lipase activity | triglyceride lipase activity | methylumbelliferyl-acetate deacetylase activity | deacetylase activity

GO Biological Process

lipid transport | establishment of localization | cell differentiation | cholesterol ester hydrolysis involved in cholesterol transport | intracellular transport | sterol metabolic process | cellular process | organic substance catabolic process | localization | macromolecule localization | intracellular cholesterol transport | establishment of localization in cell | tissue development | cytosolic transport | xenobiotic metabolic process | catabolic process | organic cyclic compound metabolic process | epithelium development | steroid biosynthetic process | cellular lipid metabolic process | response to stimulus | monocarboxylic acid metabolic process | cellular response to xenobiotic stimulus | alcohol metabolic process | cellular localization | organic hydroxy compound transport | organic hydroxy compound metabolic process | lipid metabolic process | organic substance transport | intracellular sterol transport | sterol biosynthetic process | small molecule metabolic process | vesicle-mediated transport | biosynthetic process | sterol transport | cholesterol biosynthetic process | lipid biosynthetic process | response to toxic substance | cholesterol transport | response to xenobiotic stimulus | vesicle-mediated cholesterol transport | carboxylic acid metabolic process | medium-chain fatty acid metabolic process | anatomical structure development | metabolic process | lipid localization | cholesterol metabolic process | lipid catabolic process | organic substance metabolic process | fatty acid metabolic process | steroid metabolic process | organic acid metabolic process | developmental process | epithelial cell differentiation | cellular metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | endomembrane system | endoplasmic reticulum lumen | extracellular region | membrane-bounded organelle | organelle | extracellular space | membrane-enclosed lumen | cytosol | intracellular