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QuickView for CFD (gene)


Gene Symbol:
CFD Homo sapiens Homo sapiens
Full name:
complement factor D
Synonyms:
ADIPSIN, ADN, DF, PFD, complement factor D, C3 convertase activator, D component of complement (adipsin), complement factor D preproprotein, properdin factor D
Genomic Location:
Chr 19: 810665-814624
Description:
This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mut...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Cytogenetic Map:
chr 19
19p13.3





GO Molecular Function

hydrolase activity | catalytic activity | serine hydrolase activity | serine-type endopeptidase activity | serine-type peptidase activity | endopeptidase activity | peptidase activity

GO Biological Process

positive regulation of immune response | exocytosis | neutrophil activation | proteolysis | complement activation | establishment of localization | regulation of immune system process | platelet degranulation | defense response | cellular process | secretion | leukocyte degranulation | localization | regulation of immune response | leukocyte activation | response to stimulus | neutrophil degranulation | positive regulation of immune system process | response to stress | leukocyte activation involved in immune response | secretion by cell | nitrogen compound metabolic process | leukocyte mediated immunity | complement activation, alternative pathway | vesicle-mediated transport | regulated exocytosis | protein activation cascade | humoral immune response | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | activation of immune response | protein metabolic process | metabolic process | immune response | organic substance metabolic process | serine-type endopeptidase activity | serine-type peptidase activity | cell activation | endopeptidase activity | innate immune response | neutrophil mediated immunity | immune system process | peptidase activity | macromolecule metabolic process

GO Cellular Component

secretory granule | cytoplasmic vesicle | cell | cytoplasmic vesicle lumen | cytoplasm | intracellular organelle | platelet alpha granule | ficolin-1-rich granule lumen | secretory vesicle | endomembrane system | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | membrane-enclosed lumen | secretory granule lumen | intracellular vesicle | intracellular | platelet alpha granule lumen | vesicle lumen