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QuickView for CGRP-I (gene)


Gene Symbol:
CALCA Homo sapiens Homo sapiens
Full name:
calcitonin related polypeptide alpha
Synonyms:
CALC1, CGRP, CGRP-I, CGRP1, CT, KC, PCT, calcitonin, calcitonin gene-related peptide 1, alpha-type CGRP, calcitonin 1, calcitonin gene-related peptide I, calcitonin/calcitonin-related polypeptide, alpha, katacalcin
Genomic Location:
Chr 11: 14944792-14950408
Description:
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vas...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 11
11p15.2





GO Molecular Function

signaling receptor binding | hormone activity | molecular function regulator | identical protein binding | protein binding | receptor regulator activity | G-protein coupled receptor binding | receptor ligand activity | calcitonin receptor binding

GO Biological Process

regulation of blood vessel diameter | regulation of muscle system process | detection of stimulus | response to cytokine | cell motility | intracellular signal transduction | negative regulation of muscle contraction | negative regulation of cellular process | negative regulation of RNA biosynthetic process | cellular response to tumor necrosis factor | negative regulation of tissue remodeling | defense response | regulation of smooth muscle contraction | cellular chemical homeostasis | positive regulation of phosphate metabolic process | regulation of bone remodeling | cellular process | neuropeptide signaling pathway | localization | cellular homeostasis | female pregnancy | negative regulation of nucleic acid-templated transcription | positive regulation of protein kinase activity | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of neurological system process | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | neurological system process involved in regulation of systemic arterial blood pressure | response to nerve growth factor | positive regulation of cellular protein metabolic process | negative regulation of bone resorption | calcium ion homeostasis | response to stimulus | response to pain | positive regulation of protein metabolic process | regulation of blood vessel size | negative regulation of neurological system process | response to stress | regulation of blood circulation | sensory perception of temperature stimulus | regulation of heart rate | reproduction | response to temperature stimulus | hormone activity | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | monocyte chemotaxis | regulation of systemic arterial blood pressure by baroreceptor feedback | cell chemotaxis | activation of protein kinase activity | molecular function regulator | metal ion homeostasis | negative regulation of blood pressure | detection of temperature stimulus involved in sensory perception | leukocyte migration | regulation of nucleic acid-templated transcription | detection of abiotic stimulus | locomotion | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | multicellular organism development | cell migration | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of muscle contraction | regulation of catalytic activity | cellular response to nerve growth factor stimulus | regulation of phosphorylation | regulation of ossification | regulation of gene expression | nervous system process | regulation of blood pressure | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | second-messenger-mediated signaling | cellular response to cytokine stimulus | sensory perception of pain | regulation of cellular protein metabolic process | positive regulation of ossification | detection of temperature stimulus involved in sensory perception of pain | regulation of heart contraction | cation homeostasis | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | inflammatory response | cyclic-nucleotide-mediated signaling | regulation of protein metabolic process | leukocyte chemotaxis | cellular calcium ion homeostasis | homeostatic process | regulation of protein phosphorylation | regulation of RNA metabolic process | regulation of tube size | positive regulation of molecular function | regulation of signaling receptor activity | activation of adenylate cyclase activity | receptor regulator activity | multicellular organismal response to stress | protein metabolic process | positive regulation of protein modification process | response to organic substance | cAMP-mediated signaling | regulation of kinase activity | detection of stimulus involved in sensory perception | negative regulation of ossification | anatomical structure development | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | vasodilation | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | regulation of tube diameter | regulation of bone resorption | regulation of tissue remodeling | chemical homeostasis | behavior | receptor ligand activity | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | positive regulation of kinase activity | response to heat | ion homeostasis | regulation of phosphate metabolic process | phospholipase C-activating G-protein coupled receptor signaling pathway | sensory perception | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | signaling | feeding behavior | regulation of transcription, DNA-templated | negative regulation of systemic arterial blood pressure | positive regulation of phosphorylation | cellular protein metabolic process | artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure | developmental process | detection of temperature stimulus | cellular metal ion homeostasis | negative regulation of smooth muscle contraction | embryo implantation | negative regulation of bone remodeling | positive regulation of metabolic process | immune system process | cellular metabolic process | response to tumor necrosis factor | cellular response to organic substance | positive regulation of blood vessel diameter | aging | chemotaxis | divalent inorganic cation homeostasis | signal transduction | mononuclear cell migration | regulation of signaling | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | distal axon | terminal bouton | cytoplasm | intracellular organelle | presynapse | cell projection | extracellular region | membrane-bounded organelle | nucleus | organelle | axon terminus | extracellular space | axon | neuron projection terminus | intracellular