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QuickView for CHD3 (gene)

Gene Symbol:
CHD3 Homo sapiens Homo sapiens
Full name:
chromodomain helicase DNA binding protein 3
Mi-2a, Mi2-ALPHA, ZFH, chromodomain-helicase-DNA-binding protein 3, ATP-dependent helicase CHD3, CHD-3, hZFH, mi-2 autoantigen 240 kDa protein, zinc finger helicase, zinc-finger helicase (Snf2-like)
Genomic Location:
Chr 17: 7728849-7756246
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin b...
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 17

GO Molecular Function

cation binding | nucleic acid binding | ribonucleotide binding | ATP-dependent DNA helicase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | protein deacetylase activity | catalytic activity | ATP binding | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | anion binding | adenyl nucleotide binding | histone deacetylase activity | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | purine nucleotide binding | ATP-dependent helicase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | DNA helicase activity | protein binding | zinc ion binding | hydrolase activity, acting on acid anhydrides | transition metal ion binding | purine ribonucleotide binding | adenyl ribonucleotide binding | deacetylase activity | DNA-dependent ATPase activity | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | helicase activity | drug binding | metal ion binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | RNA binding

GO Biological Process

RNA metabolic process | histone modification | microtubule cytoskeleton organization | histone deacetylation | microtubule-based process | cellular process | chromatin organization | microtubule organizing center organization | DNA geometric change | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | ATP-dependent DNA helicase activity | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | protein modification process | protein deacetylase activity | cellular biosynthetic process | macromolecule modification | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | histone deacetylase activity | cell cycle | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | protein deacetylation | aromatic compound biosynthetic process | DNA duplex unwinding | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA helicase activity | protein metabolic process | centrosome cycle | chromatin assembly or disassembly | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | cytoskeleton organization | transcription, DNA-templated | covalent chromatin modification | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | organelle organization | cellular protein modification process | DNA conformation change | heterocycle metabolic process | chromosome organization | cellular metabolic process | spindle organization | macromolecule metabolic process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | catalytic complex | microtubule organizing center | cell | nuclear lumen | nuclear transcriptional repressor complex | nucleolus | cytoplasm | intracellular organelle | centrosome | protein-containing complex | histone deacetylase complex | nucleoplasm | chromatin | nuclear chromosome | microtubule cytoskeleton | membrane-bounded organelle | transcriptional repressor complex | nucleus | organelle | SWI/SNF superfamily-type complex | NuRD complex | membrane-enclosed lumen | nuclear chromatin | ATPase complex | cytoskeleton | intracellular