QuickView for CHRM2 (gene)

Gene Symbol:

CHRM2 Homo sapiens

Full name:

cholinergic receptor muscarinic 2

Synonyms:

HM2, muscarinic acetylcholine receptor M2, 7TM receptor, acetylcholine receptor, muscarinic 2, cholinergic receptor, muscarinic 2, muscarinic M2 receptor

Genomic Location:

Chr 7: 136203939-136352311

Description:

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic rece...

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The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TATAAA_TATA_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-20

Cytogenetic Map:

7q33

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