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QuickView for CHRNA3 (gene)


Gene Symbol:
CHRNA3 Homo sapiens Homo sapiens
Full name:
cholinergic receptor nicotinic alpha 3 subunit
Synonyms:
LNCR2, NACHRA3, PAOD2, neuronal acetylcholine receptor subunit alpha-3, cholinergic receptor, nicotinic alpha 3, cholinergic receptor, nicotinic, alpha 3 (neuronal), cholinergic receptor, nicotinic, alpha polypeptide 3, neuronal nicotinic acetylcholine receptor, alpha3 subunit
Genomic Location:
Chr 15: 76674706-76700377
Description:
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that lik...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Cytogenetic Map:
chr 15
15q25.1





GO Molecular Function

transmitter-gated ion channel activity | acetylcholine-gated cation-selective channel activity | neurotransmitter receptor activity | cation binding | passive transmembrane transporter activity | neurotransmitter binding | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | cation transmembrane transporter activity | acetylcholine receptor activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | ion binding | acetylcholine binding | hormone binding | protein binding | excitatory extracellular ligand-gated ion channel activity | cation channel activity | inorganic cation transmembrane transporter activity | channel activity | drug binding | ion channel activity | substrate-specific channel activity

GO Biological Process

transmitter-gated ion channel activity | regulation of muscle system process | regulation of cell morphogenesis | regulation of neurogenesis | regulation of cellular localization | acetylcholine-gated cation-selective channel activity | regulation of cell development | regulation of localization | establishment of localization | response to hormone | cell differentiation | excitatory postsynaptic potential | nervous system development | regulation of smooth muscle contraction | response to drug | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | cellular process | localization | passive transmembrane transporter activity | acetylcholine receptor signaling pathway | chemical synaptic transmission | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | regulation of acetylcholine secretion, neurotransmission | transmembrane transporter activity | positive regulation of cellular protein metabolic process | ligand-gated ion channel activity | cellular component organization | behavioral response to nicotine | response to stimulus | ion gated channel activity | activation of transmembrane receptor protein tyrosine kinase activity | positive regulation of protein metabolic process | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | regulation of response to drug | cellular component assembly | modulation of chemical synaptic transmission | cell-cell signaling | activation of protein kinase activity | cell surface receptor signaling pathway involved in cell-cell signaling | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | regulation of membrane potential | regulation of neurotransmitter levels | response to nitrogen compound | cellular response to hormone stimulus | response to nicotine | system development | regulation of synaptic transmission, cholinergic | multicellular organism development | regulation of muscle contraction | regulation of catalytic activity | regulation of phosphorylation | regulation of hormone levels | ion transmembrane transport | regulation of hormone secretion | cellular response to ammonium ion | regulation of neuron differentiation | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | cation transmembrane transporter activity | excretion | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | response to ammonium ion | response to acetylcholine | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | ion transmembrane transporter activity | locomotory behavior | regulation of cellular protein metabolic process | extracellular ligand-gated ion channel activity | cellular protein-containing complex assembly | response to toxic substance | cellular response to drug | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | neuromuscular synaptic transmission | regulation of protein phosphorylation | positive regulation of molecular function | cation transmembrane transport | protein-containing complex assembly | regulation of cell morphogenesis involved in differentiation | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | anatomical structure development | regulation of dendrite morphogenesis | cell surface receptor signaling pathway | regulation of secretion | behavior | excitatory extracellular ligand-gated ion channel activity | positive regulation of kinase activity | micturition | regulation of phosphate metabolic process | renal system process | cation channel activity | adult behavior | regulation of dendrite development | regulation of cell communication | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | positive regulation of phosphorylation | cation transport | channel activity | regulation of nervous system development | regulation of developmental process | regulation of ion transport | developmental process | regulation of transport | synaptic transmission, cholinergic | serotonin receptor signaling pathway | ion channel activity | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | ion transport | regulation of cell projection organization | synaptic transmission involved in micturition | cellular response to organic substance | substrate-specific channel activity | regulation of cellular component organization | signal transduction | regulation of signaling | regulation of neurotransmitter secretion | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | dendrite | synapse | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | receptor complex | membrane microdomain | dendritic tree | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane | membrane raft | postsynaptic density | asymmetric synapse | integral component of plasma membrane | organelle | postsynaptic specialization | cell periphery | transmembrane transporter complex | plasma membrane raft | ion channel complex | cell junction | acetylcholine-gated channel complex | membrane | intrinsic component of plasma membrane