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QuickView for CHRNA6 (gene)


Gene Symbol:
CHRNA6 Homo sapiens Homo sapiens
Full name:
cholinergic receptor nicotinic alpha 6 subunit
Synonyms:
CHNRA6, neuronal acetylcholine receptor subunit alpha-6, acetylcholine receptor, nicotinic, alpha 6 (neuronal), cholinergic receptor, nicotinic alpha 6, cholinergic receptor, nicotinic, alpha 6 (neuronal), cholinergic receptor, nicotinic, alpha polypeptide 6
Genomic Location:
Chr 8: 42726920-42742776
Description:
This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exoge...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 8
8p11.21


Transcripts Names
NM_004198
NM_001199279
Protein Names
B2R8V4
B4DQH1
Q15825



GO Molecular Function

neurotransmitter receptor activity | cation binding | passive transmembrane transporter activity | neurotransmitter binding | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | acetylcholine receptor activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | ion binding | acetylcholine binding | hormone binding | protein binding | channel activity | drug binding | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of localization | establishment of localization | excitatory postsynaptic potential | response to drug | cellular process | regulation of catecholamine secretion | localization | passive transmembrane transporter activity | chemical synaptic transmission | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | response to stimulus | ion gated channel activity | regulation of response to drug | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of membrane potential | response to nicotine | ion transmembrane transport | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | response to toxic substance | cell communication | neuromuscular synaptic transmission | regulation of dopamine secretion | cell surface receptor signaling pathway | regulation of secretion | membrane depolarization | transmembrane transport | signaling | channel activity | regulation of ion transport | regulation of transport | synaptic transmission, cholinergic | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | synapse | neuron projection | cell | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | receptor complex | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane | integral component of plasma membrane | cell periphery | transmembrane transporter complex | ion channel complex | cell junction | acetylcholine-gated channel complex | membrane | intrinsic component of plasma membrane