QuickView for CHRNB1 (gene)

Gene Symbol:

CHRNB1 Homo sapiens

Full name:

cholinergic receptor nicotinic beta 1 subunit

Synonyms:

ACHRB, CHRNB, CMS1D, CMS2A, CMS2C, SCCMS, acetylcholine receptor subunit beta, acetylcholine receptor, nicotinic, beta 1 (muscle), cholinergic receptor, nicotinic beta 1, cholinergic receptor, nicotinic, beta 1 (muscle), cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)

Genomic Location:

Chr 17: 7289130-7301656

Description:

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane...

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The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GCANCTGNY_MYOD_Q6 ,  GATAAGR_GATA_C ,  E2A_Q2 ,  TATAAA_TATA_01 ,  GGGYGTGNY_UNKNOWN ,  CAGGTG_E12_Q6 ,  E47_02 ,  MYOD_Q6 ,  GGGCGGR_SP1_Q6 ,  AREB6_03 ,  ACCTGTTG_UNKNOWN

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Cytogenetic Map:

17p13.1

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