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QuickView for CHRNB4 (gene)


Gene Symbol:
CHRNB4 Homo sapiens Homo sapiens
Full name:
cholinergic receptor nicotinic beta 4 subunit
Synonyms:
neuronal acetylcholine receptor subunit beta-4, acetylcholine receptor, nicotinic, beta 4 (neuronal), cholinergic receptor, nicotinic, beta 4 (neuronal), cholinergic receptor, nicotinic, beta polypeptide 4, neuronal nicotinic receptor beta 4 subunit
Genomic Location:
Chr 15: 76703691-76720642
Description:
This gene is found within a conserved gene cluster and encodes one of the beta subunits of the nicotinic acetylcholine receptor (nAChRs) superfamily which form ligand-gated ion channels with a central pore that forms a cation channel. Neuronal nAChRs are pentameric structures that can be either homomeric or heteromeric, with heteromeric structures ...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 15
15q25.1





GO Molecular Function

transmitter-gated ion channel activity | acetylcholine-gated cation-selective channel activity | neurotransmitter receptor activity | cation binding | passive transmembrane transporter activity | neurotransmitter binding | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | cation transmembrane transporter activity | acetylcholine receptor activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | protein heterodimerization activity | extracellular ligand-gated ion channel activity | ion binding | acetylcholine binding | hormone binding | protein binding | protein dimerization activity | excitatory extracellular ligand-gated ion channel activity | cation channel activity | inorganic cation transmembrane transporter activity | channel activity | drug binding | ion channel activity | substrate-specific channel activity

GO Biological Process

transmitter-gated ion channel activity | regulation of muscle system process | exocytosis | regulation of transmission of nerve impulse | neutrophil activation | regulation of cellular localization | acetylcholine-gated cation-selective channel activity | regulation of localization | establishment of localization | excitatory postsynaptic potential | regulation of smooth muscle contraction | response to drug | positive regulation of neurological system process | cellular process | secretion | leukocyte degranulation | localization | passive transmembrane transporter activity | chemical synaptic transmission | regulation of neurological system process | regulation of cellular process | leukocyte activation | transmembrane transporter activity | ligand-gated ion channel activity | smooth muscle contraction | cellular component organization | behavioral response to nicotine | muscle contraction | response to stimulus | ion gated channel activity | neutrophil degranulation | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | leukocyte activation involved in immune response | secretion by cell | cellular component assembly | modulation of chemical synaptic transmission | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | regulation of membrane potential | regulation of neurotransmitter levels | response to nicotine | protein complex oligomerization | leukocyte mediated immunity | regulation of muscle contraction | ion transmembrane transport | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | cation transmembrane transporter activity | excretion | vesicle-mediated transport | ion transmembrane transporter activity | locomotory behavior | extracellular ligand-gated ion channel activity | regulated exocytosis | response to toxic substance | cell communication | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | neuromuscular synaptic transmission | cation transmembrane transport | protein-containing complex assembly | positive regulation of transmission of nerve impulse | cell surface receptor signaling pathway | regulation of secretion | behavior | immune response | excitatory extracellular ligand-gated ion channel activity | micturition | renal system process | cell activation | cation channel activity | adult behavior | regulation of cell communication | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | protein heterooligomerization | cation transport | channel activity | regulation of transport | synaptic transmission, cholinergic | neutrophil mediated immunity | ion channel activity | ion transport | synaptic transmission involved in micturition | immune system process | substrate-specific channel activity | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | regulation of neurotransmitter secretion | multicellular organismal process

GO Cellular Component

secretory granule | integral component of membrane | synapse | neuron projection | organelle membrane | tertiary granule | cytoplasmic vesicle | cell | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | cytoplasm | intracellular organelle | receptor complex | secretory granule membrane | protein-containing complex | cell projection | secretory vesicle | postsynaptic membrane | endomembrane system | postsynapse | plasma membrane | vesicle | specific granule | integral component of plasma membrane | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | transmembrane transporter complex | tertiary granule membrane | ion channel complex | intracellular vesicle | intracellular | cell junction | specific granule membrane | acetylcholine-gated channel complex | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane