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QuickView for CLCA2;jsessionid=53CA6A2F744C5C7317278616728B444B (gene)


Gene Symbol:
CLCA2 Homo sapiens Homo sapiens
Full name:
chloride channel accessory 2
Synonyms:
CACC, CACC3, CLCRG2, CaCC-3, calcium-activated chloride channel regulator 2, CLCA family member 2, chloride channel regulator, calcium-activated chloride channel protein 3, chloride channel, calcium activated, family member 2
Genomic Location:
Chr 1: 86662413-86694829
Description:
This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. The encoded protein is autoproteolytically processed to generate N- and C- terminal fragments. Expression of this gene is upregulated by the tumor suppressor ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris Pan troglodytes Gallus gallus
External Links:
Entrez Gene
Cytogenetic Map:
chr 1
1p22.3


Transcripts Names
NM_006536
XM_011542448
Protein Names
Q9UQC9
Q9Y6N2
A8K2T3



GO Molecular Function

metallopeptidase activity | anion transmembrane transporter activity | cation binding | metalloendopeptidase activity | passive transmembrane transporter activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | hydrolase activity | chloride channel activity | intracellular calcium activated chloride channel activity | inorganic anion transmembrane transporter activity | catalytic activity | chloride transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | ion binding | anion channel activity | endopeptidase activity | channel activity | metal ion binding | ion channel activity | peptidase activity | substrate-specific channel activity

GO Biological Process

metallopeptidase activity | proteolysis | establishment of localization | anion transmembrane transporter activity | localization | metalloendopeptidase activity | passive transmembrane transporter activity | anion transport | transmembrane transporter activity | ligand-gated ion channel activity | chloride transmembrane transport | ion gated channel activity | chloride channel activity | chloride transport | inorganic anion transport | intracellular calcium activated chloride channel activity | inorganic anion transmembrane transporter activity | nitrogen compound metabolic process | chloride transmembrane transporter activity | ion transmembrane transport | ion transmembrane transporter activity | protein metabolic process | anion transmembrane transport | metabolic process | anion channel activity | cell adhesion | organic substance metabolic process | transmembrane transport | endopeptidase activity | channel activity | ion channel activity | ion transport | peptidase activity | substrate-specific channel activity | macromolecule metabolic process

GO Cellular Component

integral component of membrane | basal plasma membrane | intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | basal part of cell | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endomembrane system | plasma membrane | nuclear envelope | integral component of plasma membrane | extracellular region | membrane-bounded organelle | nucleus | organelle | cell periphery | basolateral plasma membrane | cytosol | intracellular | cell junction | membrane | intrinsic component of plasma membrane