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QuickView for CLEC4M (gene)


Gene Symbol:
CLEC4M Homo sapiens Homo sapiens
Full name:
C-type lectin domain family 4 member M
Synonyms:
CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, L-SIGN, LSIGN, C-type lectin domain family 4 member M, CD209 antigen-like protein 1, CD299 antigen, DC-SIGN-related protein, dendritic cell-specific ICAM-3-grabbing non-integrin 2, liver/lymph node-specific ICAM-3 grabbing non-integrin, mannose binding C-type lectin DC-SIGNR
Genomic Location:
Chr 19: 7734081-7740491
Description:
This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health....
Orthologs:
Mus musculus Rattus norvegicus Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 19
19p13.2





GO Molecular Function

peptide binding | cation binding | transmembrane signaling receptor activity | monosaccharide binding | peptide antigen binding | amide binding | signaling receptor activity | calcium-dependent protein binding | ICAM-3 receptor activity | antigen binding | mannose binding | ion binding | carbohydrate binding | protein binding | virion binding | virus receptor activity | metal ion binding | small molecule binding

GO Biological Process

adaptive immune response | antigen processing and presentation | intracellular signal transduction | establishment of localization | defense response | virion attachment to host cell | cellular process | localization | interspecies interaction between organisms | cell recognition | regulation of cellular process | entry into host cell | viral life cycle | response to stimulus | peptide antigen transport | response to stress | intracellular transport of virus | adhesion of symbiont to host | viral entry into host cell | organic substance transport | viral genome replication | modification of morphology or physiology of other organism | cell-cell recognition | peptide transport | vesicle-mediated transport | cell communication | adhesion of symbiont to host cell | viral process | import into cell | leukocyte cell-cell adhesion | amide transport | endocytosis | cell adhesion | immune response | virus receptor activity | cell-cell adhesion | signaling | modulation by virus of host morphology or physiology | innate immune response | antigen processing and presentation of peptide antigen | immune system process | signal transduction

GO Cellular Component

integral component of membrane | host cell | cell | intrinsic component of membrane | other organism cell | cytoplasm | plasma membrane | integral component of plasma membrane | extracellular region | cell periphery | intracellular | membrane | intrinsic component of plasma membrane