QuickView for CLTA (gene)

Gene Symbol:

CLTA Homo sapiens

Full name:

clathrin light chain A

Synonyms:

LCA, clathrin light chain A, clathrin, light polypeptide (Lca)

Genomic Location:

Chr 9: 36180892-36202056

Description:

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function a...

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Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  GATA1_01 ,  VDR_Q6 ,  ALPHACP1_01 ,  ETS2_B ,  NFY_01 ,  ATGTTTC_MIR494 ,  NFY_Q6 ,  E2F1DP1RB_01 ,  AACTTT_UNKNOWN ,  E2F_Q3 ,  ACACTAC_MIR1423P

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-142-3p ,  Predicted Gene Targets for miR-485-5p ,  Predicted Gene Targets for miR-494

Cytogenetic Map:

9p13.3

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