QuickView for CMPK1 (gene)
- Gene Symbol:
- CMPK1
Homo sapiens - Full name:
- cytidine/uridine monophosphate kinase 1
- Synonyms:
- CK, CMK, CMPK, UMK, UMP-CMPK, UMPK, UMP-CMP kinase, UMP/CMP kinase, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic, cytidylate kinase, dCMP kinase, deoxycytidylate kinase, nucleoside-diphosphate kinase, uridine monophosphate kinase, uridine monophosphate/cytidine monophosphate kinase
- Genomic Location:
- Chr 1: 47572175-47617098
- Description:
-
This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-130 , Predicted Gene Targets for miR-133 , Predicted Gene Targets for miR-143 , Predicted Gene Targets for miR-15 , Predicted Gene Targets for miR-20 , Predicted Gene Targets for miR-330 , Predicted Gene Targets for miR-503 , Predicted Gene Targets for miR-124a , Predicted Gene Targets for miR-29
- Cytogenetic Map:
-
1p33
GO Molecular Function
nucleoside monophosphate kinase activity | uridylate kinase activity | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | catalytic activity | ATP binding | anion binding | nucleoside kinase activity | adenyl nucleotide binding | purine nucleotide binding | uridine kinase activity | ion binding | nucleobase-containing compound kinase activity | organic cyclic compound binding | purine ribonucleoside triphosphate binding | nucleoside diphosphate kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, phosphate group as acceptor | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding | cytidylate kinase activity
GO Biological Process
pyrimidine nucleoside biosynthetic process | pyrimidine nucleoside metabolic process | nucleoside monophosphate kinase activity | uridylate kinase activity | cellular process | nucleotide metabolic process | ribose phosphate metabolic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | nucleoside monophosphate phosphorylation | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | pyrimidine nucleotide metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | cellular biosynthetic process | nucleotide biosynthetic process | nitrogen compound metabolic process | phosphorus metabolic process | ribonucleoside monophosphate biosynthetic process | nucleoside kinase activity | organophosphate metabolic process | nucleotide phosphorylation | nucleoside metabolic process | small molecule metabolic process | pyrimidine nucleotide biosynthetic process | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | phosphorylation | uridine kinase activity | nucleobase-containing compound kinase activity | nucleoside triphosphate biosynthetic process | pyrimidine nucleobase biosynthetic process | pyrimidine ribonucleoside biosynthetic process | phosphate-containing compound metabolic process | nucleoside diphosphate kinase activity | nucleobase-containing small molecule interconversion | nucleoside diphosphate metabolic process | UMP biosynthetic process | 'de novo' pyrimidine nucleobase biosynthetic process | metabolic process | pyrimidine ribonucleotide biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | pyrimidine nucleobase metabolic process | ribose phosphate biosynthetic process | kinase activity | carbohydrate derivative metabolic process | heterocycle metabolic process | cellular metabolic process | nucleoside diphosphate phosphorylation | nucleoside monophosphate biosynthetic process | cytidylate kinase activity
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | membrane-enclosed lumen | cytosol | intracellular
