QuickView for CNOT9;jsessionid=CEEF0A028C9D537A47EF2A4EB245F2F2 (gene)
- Gene Symbol:
- CNOT9
Homo sapiens - Full name:
- CCR4-NOT transcription complex subunit 9
- Synonyms:
- CAF40, CT129, RCD-1, RCD1, RQCD1, CCR4-NOT transcription complex subunit 9, cell differentiation protein RCD1 homolog, RCD1 required for cell differentiation1 homolog, cancer/testis antigen 129, cell differentiation protein RQCD1 homolog, protein involved in sexual development
- Genomic Location:
- Chr 2: 219141922-219167243
- Description:
-
This gene encodes a member of the highly conserved RCD1 protein family. The encoded protein is a transcriptional cofactor and a core protein of the CCR4-NOT complex. It may be involved in signal transduction as well as retinoic acid-regulated cell differentiation and development. Alternatively spliced transcript variants have been described for thi...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
HNF4ALPHA_Q6 , PPARG_01 , AREB6_02 , E2F4DP1_01 , COUP_01 , EGR2_01 , TGACCTY_ERR1_Q2 , HNF4_DR1_Q3 , E2F_Q6 , E2F1_Q6_01
- Cytogenetic Map:
-
2q35
| Transcripts Names |
|---|
| NM_005444 |
| NM_001271634 |
| NM_001271635 |
| NR_073390 |
| XM_017005249 |
| XM_011512138 |
| XM_017005248 |
GO Molecular Function
kinase binding | enzyme binding | signaling receptor binding | protein domain specific binding | identical protein binding | protein binding | protein homodimerization activity | protein dimerization activity | epidermal growth factor receptor binding | growth factor receptor binding
GO Biological Process
RNA metabolic process | gene silencing by RNA | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | response to cytokine | developmental process involved in reproduction | intracellular signal transduction | regulation of cell cycle G1/S phase transition | negative regulation of cellular process | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | regulation of G1/S transition of mitotic cell cycle | positive regulation of phosphate metabolic process | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | mitotic DNA integrity checkpoint | negative regulation of signaling | positive regulation of peptidyl-serine phosphorylation | negative regulation of G1/S transition of mitotic cell cycle | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | gene silencing | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | signal transduction involved in mitotic DNA damage checkpoint | mRNA catabolic process | response to stimulus | regulation of mitotic cell cycle phase transition | positive regulation of protein metabolic process | response to stress | regulation of intracellular steroid hormone receptor signaling pathway | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | regulation of cell cycle phase transition | reproduction | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | mRNA metabolic process | nuclear-transcribed mRNA catabolic process | cellular biosynthetic process | nucleobase-containing compound catabolic process | positive regulation of ERBB signaling pathway | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | negative regulation of mitotic cell cycle phase transition | DNA damage response, signal transduction by p53 class mediator | mitotic DNA damage checkpoint | cellular response to DNA damage stimulus | regulation of intracellular estrogen receptor signaling pathway | regulation of phosphorylation | positive regulation of cell cycle | signal transduction in response to DNA damage | regulation of gene expression | cellular response to stress | cell cycle | RNA catabolic process | regulation of cell cycle arrest | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | cytokine-mediated signaling pathway | nuclear-transcribed mRNA poly(A) tail shortening | negative regulation of intracellular steroid hormone receptor signaling pathway | cellular response to cytokine stimulus | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | signal transduction involved in cell cycle checkpoint | mitotic G1 DNA damage checkpoint | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | aromatic compound catabolic process | regulation of protein phosphorylation | regulation of RNA metabolic process | negative regulation of intracellular estrogen receptor signaling pathway | regulation of mitotic cell cycle | positive regulation of molecular function | positive regulation of cell cycle arrest | positive regulation of protein modification process | response to organic substance | G1 DNA damage checkpoint | positive regulation of nuclear receptor transcription coactivator activity | cellular macromolecule catabolic process | mitotic cell cycle | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | negative regulation of mitotic cell cycle | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of epidermal growth factor receptor signaling pathway | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | gene expression | signal transduction involved in mitotic cell cycle checkpoint | regulation of phosphate metabolic process | negative regulation of translation | transcription, DNA-templated | regulation of peptidyl-serine phosphorylation | negative regulation of cell cycle | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of cell cycle G1/S phase transition | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | regulation of ERBB signaling pathway | regulation of nuclear receptor transcription coactivator activity | positive regulation of phosphorylation | positive regulation of epidermal growth factor receptor signaling pathway | cellular macromolecule biosynthetic process | signal transduction involved in DNA damage checkpoint | developmental process | positive regulation of cell cycle process | mitotic G1/S transition checkpoint | positive regulation of nucleic acid-templated transcription | heterocycle metabolic process | signal transduction involved in mitotic G1 DNA damage checkpoint | positive regulation of metabolic process | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | cellular response to organic substance | sex differentiation | DNA damage checkpoint | regulation of translation | cell cycle checkpoint | signal transduction by p53 class mediator | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | ribonucleoprotein granule | cytoplasm | intracellular organelle | P-body | protein-containing complex | CCR4-NOT core complex | ribonucleoprotein complex | membrane-bounded organelle | nucleus | organelle | cytoplasmic ribonucleoprotein granule | CCR4-NOT complex | cytosol | intracellular | membrane
