QuickView for CNST;jsessionid=FA902B44B6859B06376DB8A60F248A89 (gene)

Gene Symbol:

CNST Homo sapiens

Full name:

consortin, connexin sorting protein

Synonyms:

C1orf71, PPP1R64, consortin, protein phosphatase 1, regulatory subunit 64

Genomic Location:

Chr 1: 244796429-244897049

Description:

Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of ga...

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Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PU1_Q6 ,  MYC_Q2 ,  YTATTTTNR_MEF2_02 ,  CACGTG_MYC_Q2 ,  GGGAGGRR_MAZ_Q6 ,  TFIII_Q6 ,  GGAANCGGAANY_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  GGCNKCCATNK_UNKNOWN ,  WCTCNATGGY_UNKNOWN ,  NMYC_01 ,  ELK1_01 ,  SCGGAAGY_ELK1_02 ,  RGAGGAARY_PU1_Q6 ,  USF2_Q6 ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-30

Cytogenetic Map:

1q44

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